摘要
目的：探讨中晚期肝癌介入治疗中导管位置与碘油用量的关系以及碘油用量对临床疗效、副作用的影响。方法：回顾采用肝固有动脉给药的病例８６例及高度选择性栓塞治疗的肝癌２５０例，并比较二者的疗效、副作用与碘油用量的关系。结果：本组病例肝癌大小 ３—１５ｃｍ，８６例为肝固有动脉给药治疗 １～３次者，碘油用量 ５—１０ｍｌ／次，肿瘤明显缩小 ２０例（２３％），２年生存 ５例（６％）。高度选择性栓塞治疗１～ ３次的 ２５０例，碘油用量 １５—４０ｍｌ次，肿瘤明显缩小 １６３例（６５％），２年生存 ７８例（３１％）。结论：肝癌超选择性栓塞的碘油用量与疗效成正比，副反应随碘油用量轻微增高；固有肝动脉栓塞疗效较差、副作用大。
Objective :To evaluate the relationship between place of catheter and amount of lipiodol and its in- fluence upon clinical effects and negative effects. Methods :86 cases of transcatheter proper hepatic arterial em- bolization and 250 cases of super selective segmental transarterial embolization(STAE) were analyzed respective- ly and curative effects and negative effects of the two and the relationship with amount of lipiodol were com- pared. Results: Liver neoplastic size of all cases were 3 - 15cm. For 86 cases of proper hepatoarterial emboliza- tion, the amount of lipiodol was 5 - 10ml. Obvious tumor shrinking occurred in 20 cases(23% ) , the 2-year sur- vival in 5 cases (6%).For 250 cases of STAE,the amount of lipiodol was 15 - 40ml. Obvious tumor shrinking occurred in 163cases (65%) ,the 2 - year survival occurred in 78 cases(31%). Conclusion :For STAE,amount of lipiodol is in direct proportion to curative effects and negative effects increase slightly as the amount of lipiodol increases. For transcatheter proper hepatic arterial embolization,curative effects were poor,negative effects were obvious.
出处
《重庆医科大学学报》
CAS
CSCD
2001年第3期282-294,共13页
Journal of Chongqing Medical University
关键词
中晚期肝癌
介入治疗
碘油量
Liver cancer
Interventional therapy
Amount of lipiodol
