摘要
目的 选取结直肠癌及非癌病例作直肠粘液Ｔ抗原检测（Ｓｈａｍ试验）与粪隐血试验的对比分析，评价直肠粘液Ｔ抗原在大肠癌早期初筛中的价值。方法对１９９７～２０００年间５２例结直肠癌及非癌病例进行直肠粘液Ｔ抗原检测及粪隐血试验。结果２９例结直肠癌病例中Ｔ抗原阳性者２６例（８９．７％）、粪隐血阳性者１５例（５１．７％），２３例非癌病变者Ｔ抗原阳性８例（３４．８％）、粪隐血阳性１１例（４７．８％）。结论直肠粘液Ｔ抗原检测可以取代粪隐血试验成为大肠癌普查的新方法。
Objective :To detect the value of rectal mucus for T-antigen in disagnosis of colorectal cancer. Methods Twenty-nine patients with large bowel cancer, twenty-nine with non-malignant disease and twenty normal subjects were studied by testing rectal mucus for T-antigen. Results A positive response was observed in 26 patients(89. 7% ) with large bowel cancer, 8 patients(34. 8% ) with non-malignant diseases. Normal subjects showed a 90% negative reaction. In the present study, the sensitivity to cancer was 89. 7%, specificity, 76. 7% and predictive value of positive test 72. 2%. Conclusion This method is high-sensitive and simple, proved useful for mass screening of colorectal cancer.
出处
《皖南医学院学报》
CAS
2001年第2期152-153,共2页
Journal of Wannan Medical College
