期刊文献+

氯沙坦、氢氯噻嗪联合治疗原发性高血压的临床观察 被引量:4

下载PDF
导出
摘要 目的:观察氯沙坦与氢氯噻嗪联合治疗原发性高血压患者的起效时间、疗效及不良反应等。方法:通过57例原发性高血压患者自身前后对照的开放性临床试验,在停用原降压药1周后即给予氯沙坦50mg和氢氯噻嗪12.5mg联合治疗,连续治疗4周,观察血压、心率、血钾、不良反应等指标。结果:两药联合应用可以比较迅速而有效的降低血压,第1周有效率可达63.2%,到第4周总有效率达92.8%。患者的耐受性好,不良反应小。结论:两药联合治疗原发性高血压是值得临床推荐的用药方式。
出处 《国外医学(心血管疾病分册)》 2001年第3期166-168,共3页
  • 相关文献

参考文献6

  • 1Weir MR,Elkins M,Liss C,et al.Efficacy, tolerability and quality of life of losartan, alone or with hydrochlorothiazide, versus nifedipine GITS in patients with essential hypertension[].Clinical Therapeutics.1996 被引量:1
  • 2Hansson L,Zanchetti A,Carruthers SG,et al.Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial[].The Lancet.1998 被引量:1
  • 3Oparil S,Barr E,Elkins M,et al.Efficacy, tolerability and quality of life of losartan, alone or with hydrochlorothiazide, versus amlodipine, alone or with hydrochlorothiazide in patients with essential hypertension[].Clinical Therapeutics.1996 被引量:1
  • 4MacKay JH,Arcuri KE,Goldberg AI,et al.Losartan and low-dose hydrochlorothiazide in patients with essential hypertension[].Archives of Internal Medicine.1996 被引量:1
  • 5Goa KL,Wagstaff AJ.Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension[].Drugs.1996 被引量:1
  • 6Goldberg AI,Dunlay MC,Sweet CS.Safety and tolerability of losartan potassium, an angiotension Ⅱ receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension[].The American Journal of Cardiology.1995 被引量:1

同被引文献12

引证文献4

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部