摘要
目的 研究我国民族药观赏獐牙菜 (SwertiadecoraFranch)的化学成分。方法 用常规的硅胶柱层析和薄层色谱法进行分离 ,根据化合物的理化性质及一维、二维波谱解析鉴定其结构。结果 从观赏獐牙菜脂溶性部分得到 6个化合物 ,分别鉴定为 1 羟基 4,5 ,6 ,7 四甲氧基酮 (swertiadecoraxanthone Ⅰ ) (Ⅰ ) ;1,3,8 三羟基 2 ,5 二甲氧基酮 (Ⅱ ) ;1,8 二羟基 3,7 二甲氧基酮 (methylswertianin ,Ⅲ ) ;1 羟基 3 ,7,8 三氧甲基酮 (decussatin ,Ⅳ ) ;1,7,8 三羟基 3 甲氧基酮 (swertianin ,Ⅴ )及二十四烷酸 (tetracosanoicacidⅥ )。结论 化合物Ⅱ为新化合物 ,定名为观赏獐牙菜酮 Ⅱ (swertiadecoraxanthone Ⅱ ) 。
OBJECTIVE To study the chemical constituents of Swertia decora Franch,a traditional herb medication in China.METHODS The constituents were separated and purified by using column chromatography with silica gel.Their structures were identified on the basis of spectral analysis and chemical reactions.RESULTS Six compounds were isolated from the CHCl 3 part of the extracts.Their structures were determined as 1 hydroxy 4,5,6,7 tetramethoxyxanthone(swertiadecoraxanthone Ⅰ)(Ⅰ),1,3,8 trihydroxy 2,5 dimethoxyxanthone(Ⅱ),1,8 dihydroxy 3,7 dimethoxy xanthone (methylswertianin,Ⅲ),1 hydroxy 3,7,8 trimethoxyxanthone (decussatin,Ⅳ),1,7,8 trihydroxy 3 methoxyxanthone(swertianin,Ⅴ) and tetracosanoic acid(Ⅵ),respectively.CONCLUSION Ⅱ named as swertiadecoraxanthone Ⅱ was a new compound and the others were found from this plant for the first time.
出处
《中国药学杂志》
EI
CAS
CSCD
北大核心
2001年第5期302-304,共3页
Chinese Pharmaceutical Journal
