摘要
目的 :对比观察硬膜外麻醉合并寒战的药物治疗效果与不良反应。方法 :60例ASAI级行下胸、腰段硬膜外麻醉合并寒战患者随机分成Ⅰ组 (静注哌替啶 )、Ⅱ组 (静注哌替啶 +氟哌啶 )和Ⅲ组 (静注曲马多 )。记录用药后寒战停止所需的时间。结果 :三组消除寒战的总有效率分别为85%、95%和 95%。Ⅱ、Ⅲ组制止寒战所需时间显著快于Ⅰ组 (P <0 .0 1)。寒战消除后动脉血氧饱和度 (SpO2 )均明显改善 (P <0 .0 1)。结论 :三组药物均可用于治疗硬膜外麻醉期间发生的寒战 ,但曲马多镇静作用弱 ,安全性高 ,尤其适用于有心。
Objective: To evaluate the efficacy and side effect of pethidine, pethidine droperdol or tramadol in the treatment of shivering during epidural anesthesia. Methods: 60 ASA I adult shivering patients undergoing elective surgery under low thoracolumbar epidural anesthesia were allocated randomly to receiving intravenous pethidine 0.5mg/kg (group I, n=20), pethidine 0.5mg/kg and droperidol 0.05mg/kg (group II, no=20) or tramadol 2mg/kg (group III, n=20). Shivering was observed after intravenous drugs. Results: The overall effective rates in three groups were 85%, 95% and 95% respectively. The onset times in group II and group III were significantly shorter than that in group I ( P <0.01).SpO 2 was improved significantly after shivering was stopped ( P <0.01). Conclusion: All groups can cure shivering during epidural anesthesia. Tramadol was weak on sedition, which was better for the patients with heart-pulmonary function disorder than that in the other groups.
出处
《赣南医学院学报》
2001年第1期18-20,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词
哌替啶
氟哌啶
曲马多
麻醉
硬膜外
Pethidine
Droperidol
Tramadol
Epidural, anesthesia