摘要
目的 评价Ⅱ、Ⅲ期食管癌术前化疗的价值。方法 对 5 0例Ⅱ、Ⅲ期食管癌患者进行以顺铂为主的联合化疗 ,并与同期内 5 0例单纯手术患者进行比较分析 ,进一步探讨提高Ⅱ、Ⅲ期食管癌患者的远期疗效。结果 单纯手术组 5年生存率为 32 0 % ,术前化疗组 5年生存率为 46 0 % ,两组差异有显著性 (P <0 0 5 )。结论 术前化疗复发率及转移率低 ,术前化疗组 5年生存率高于单纯手术组。
Objective To evaluate the effect of preoperative chemotherapy on the prognosis of stage Ⅱ or Ⅲ patients with esophageal carcinoma.Methods From February 1991 to June 1994, 50 patients with stage Ⅱ,Ⅲ esophageal carcinoma were treated with preoperative combination (CDDP) chemotherapy and compared with 50 patients received operation alone.Results The 5 year survival rate of the operation group and preoperative chemotherapy group was 32% and 46%, respectively. The difference was statistically significant.Conclusion Preoperative chemotherapy improves survival of surgically treated esophageal cancer patients.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2001年第3期254-255,共2页
Chinese Journal of Oncology
关键词
食管肿瘤/治疗
食管肿瘤/外科学:综合治疗
Esophageal neoplasms/therapy
Esophageal neoplasms/surgery
Adjutant therapy
