摘要
目的 :观察羊膜移植在治疗眼表面疾患中的应用价值。方法 :采用保存人羊膜移植术 ,部分联合带角膜缘的板层角膜移植术治疗各类型眼表面疾患 34例 (34只眼 )。结果 :34只眼中 ,眼化学伤或热烧伤 7只眼 ,术后 6只眼重建眼表成功 ,1只眼羊膜部分融解脱落 ;蚕蚀性角膜溃疡 10只眼、复发性翼状胬肉 11只眼、角膜移植术后假性胬肉 6只眼 ,术后均未见复发。 34只眼中伴睑球粘连者 18只眼 ,16只眼恢复了良好的眼球运动功能 ,2只眼术后 1～ 3个月再次发生轻度睑球粘连。结论 :保存人羊膜无免疫原性 ,几乎不发生排斥反应 ,其具有的抗炎、抗瘢痕、抗新生血管形成作用 ,可广泛应用于眼表面疾患的修复治疗。
Objective:To evaluate the therapeutic effects of amniotic membrane transplantation (AMT) for ocular surface disorders. Methods:AMT or combined with lamella transplantation was performed on 34 eyes in 34 patients with different types of ocular surface disorders. Results:In seven eyes with ocular burns the operation of AMT for ocular surface reconstruction was successful in 6 eyes but in one eye part of amniotic membrane had dissolved and sloughed. Ten eyes with Mooren′s ulcer, 11 eyes with recurrent pterygium and 6 eyes with pseudopterygium after keratoplasty were cured after AMT. In 11 eyes of symblepharon 16 eyes restored their good function of ocular movement and 2 eyes were lightly relapsed after 1-3 months of operation. Conclusion:Preserved amniotic membrane has a role of diminishing, inflammation and inhibiting neovascularization, and has few antigenicity. Amniotic membrane transplantation can be widely used to reconstruct ocular surface.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2001年第4期310-311,347,共3页
Journal of Nanjing Medical University(Natural Sciences)
关键词
羊膜移植
角膜移植
眼表面疾患
治疗
amniotic membrane transplantation
keratoplasty
ocular surface disorder
