摘要
本文对黄芪多糖（ＡＰＳ）的制备及在治疗肝炎方面进行了临床研究。通过ＡＰＳ组与对照组临床实验结果表明：治疗组氨基酶转换率（ＡＴＬ）的复常率，Ｅ抗原（ＨＢｅｓｇ），乙肝病毒－ＤＮＡ（ＨＢＶ－ＤＮＡ），阴转率均优于对照组（Ｐ＜０．０５），对口服ＡＰＳ的肝炎患者体内诱导干扰素（ＩＦＮ）的实验结果用药后较用药前血浆中ＩＦＮ含量捉高三个滴度，与文献报导的体外实验一致。因此ＡＰＳ在抗肝炎的治疗上是很有前途的。
he astragalus root and its
polysaccharide(APS)have a lot of biological activities such as antineo-plasm,antihepatitis and
antisenility.In this paper,we reported the preparation of astragalus polysac-charide and its
therapo utic effect on hepatitis.The results showed that compared with the controlgroup,the
recovering rate of ALT,the negative reversion rate of HBeAg And HBV-DNA in the APSgroup
were significantly higher(P<0.05).The experiment in vivo showed that compared with the lev-els
before the treat ment,the induced IFN in the plasma of patients with hepatitis increased 3 titers
af-ter the treatment by oral administation APS,identical with the reported documents in vitro,Our
resultssuggested that APS have goed prospects in the theatment of hepatitis.
出处
《药物生物技术》
CAS
CSCD
1995年第2期26-28,共3页
Pharmaceutical Biotechnology
关键词
黄芪多糖
制备
肝炎
实验
Astragalus Polysaccharide
Preparation
Hepatitis
