摘要
目的 :探讨全麻预注芬太尼的先发镇痛效应。方法 :选择 40例择期全麻病人 ,随机分成试验组与对照组 (n=2 0例 ) ,术前常规用药。试验组诱导前用芬太尼 5μg/kg,对照组将芬太尼改切皮后静注 ,术中麻醉维持相同。手术结束后病人自然清醒 ,术后有镇痛药使用意愿者均使用哌替啶镇痛。结果 :两组病人一般情况及芬太尼总用量无显著性差异 (P>0 .0 5) ,试验组初次使用镇痛药时间明显延长 (P<0 .0 1 ) ,用药次数及剂量也显著少于对照组 (P<0 .0 1 ) ,试验组术后仅 7(35% )例使用哌替啶 ,而对照组使用哌替啶者达 1 5(75% )例 ,两组差异性显著 (P<0 .0 5)。结论 :全麻前预注芬太尼具有良好的先发镇痛效应。
Objective:[WT5BZ]To investigate pre emptive amalgesic effect of fentanyl injection before induction.[WT5HZ]Methods:[WT5BZ]40 patients with general anesthesia were randomly divided into test group and control group ( n =20).Fentanyl 5μg/kg iv before induction in test group and after incision in control group.After operation,all patients recovered from anesthesia naturally without any antagonist.Dolantin was administered for the patients who need it.The time,times,dose,and the cases of using dolantin were recorded.Results:There is significant difference on the time,times,dose and the cases of using dolantin between two groups,despite of their similar general status.Conclusion:Injection of fentanyl before induction has a marked effect on pre dmptive analgesia.
出处
《滨州医学院学报》
2001年第3期213-214,共2页
Journal of Binzhou Medical University
关键词
芬太尼
先发镇痛
全麻
fentanyl
pre emptive analgesia
general anaesthesia
