摘要
目的 :了解化脓性胆管炎胆汁中的主要致病菌及药物敏感情况 ,指导临床合理用药。方法 :对 5 93例化脓性胆管炎胆汁细胞培养阳性的 6 70株致病菌的分布情况及其药物敏感结果作回顾性分析。结果 :6 70株胆汁培养阳性的病原菌中革兰氏阴性杆菌 5 0 9株 (75 .9% ) ;革兰氏阳性球菌 149株 (2 2 .2 % )。革兰氏阴性杆菌对头孢他啶和亚安培南的敏感率为 78.8%和 90 .6 % ,革兰氏阳性球菌对亚安培南和万古霉素的敏感率达77.2 %和 91.3 %。结论 :化脓性胆管炎主要病原菌是大肠埃希菌 ,肺炎克雷伯菌和肠球菌。头孢他啶和亚安培南可作为治疗化脓性胆管炎的首选用药 ;
Objective:The aim of this study was to analyse the pathogenic bacteria of purulent cholangitis and their sensitivity to antibiotics.Methods:Between January 1998 and December 2000,670 pathogenic bacteria of purulent cholangitis (593 patients) and their sensitivity to antibiotics were studied retrospectively.Results:In regard to 670 pathogenic bacteria with positive biliary culture,509 (75.9%) were gram-negative bacilli,of which 155 (23.1%) were Escherichia coli,126(18.8%) were klebsiella pneumoniae.149(22.2%) were gram-positive cocci,of wihch 101(15.1%) were intestinal cocci.12(1.79%) were fungi.Gram-negative bacilli was sensitive to ceftazidine and imipenem with sensitivity of 78.8% and 90.6%,Gram-positive cocci was sensitive to imipenem and vancomycin with sensitivity of 77.2% and 91.3%. Conclusions:The main pathogenic bacteria of purulent cholangitis were Escherichia coli,Klebsiella pneumoniae and intestinal cocci.Ceftazidine and/or imipenem may be the first medicine to treat purulent cholangitis.Earlier endoscopic nose-blie drainage can reduce antibiotics' use time and dosage.
出处
《中国现代医学杂志》
CAS
CSCD
2001年第4期40-41,共2页
China Journal of Modern Medicine
关键词
化脓性胆管炎
致病菌
药物敏感
Purulent Cholangitis
Pathogenic Bacteria
Drug Sensitivity
