摘要
目的:观察赤芍总甙对小鼠实验性脑缺血的影响。方法:选用小鼠断头模型及结扎双侧颈总动脉形成的小鼠脑缺血模型。结果:赤芍总甙明显延长小鼠断头后张口喘气时间,减少脑含水量,并可有效降低脑毛细血管通透性。结论:赤芍总甙对小鼠急性实验性脑缺血具有显著的保护作用。
Objective: To investigate effects of total paeony glycoside (TPG) on cerebral ischemia mice. Methods: The models of decapi-tative mice and acute cerebral ischemia mice caused by ligation of bilateral common carotid arteries were used. Results: TPG could prolong gasp time of decapatative mice, lessen cerebral water content and decrease permeability of cerebral capillary significantly. Conclusion: TPG possesses obvious protective effects on mice of acute cerebral ischemia.
出处
《中药材》
CAS
CSCD
北大核心
2001年第2期124-126,共3页
Journal of Chinese Medicinal Materials