摘要
目的 :观察七叶皂苷对腰椎间盘突出症(LIDP)的治疗效果。方法 :176例LIDP病人分为七叶皂苷组 80例 [男性 56例 ,女性 2 4例 ,年龄 (4 3±s 17)a ,病程 (7.4± 2 .3)mo],接受常规综合治疗及七叶皂苷 10～ 15mg加入输液中iv ,drip ,bid ,连用 7～ 10d ;对照组 96例 [男性 57例 ,女性 39例 ,年龄 (4 2± 16 )a ,病程 (7± 3)mo]仅接受常规综合治疗 ,包括牵引、推拿、针灸、止痛药物等。 4wk后观察疗效。结果 :七叶皂苷组、对照组总有效率分别为95%和 81% (P <0 .0 5) ;病程 0 .5a内 2组总有效率分别为 97% ,85% (P <0 .0 5) ,无严重不良反应。结论 :七叶皂苷治疗LIDP安全、有效 ,治疗越早越好。
AIM:To observe the therapeutic effect of aescine in the treatment of lumbar intervertebral disc prolapse(LIDP).METHODS:One hundred and seventy-six patients with LIDP were divided into 2 groups:aescine group of 80 patients[M56,F24;age(43± s 17)a,course of disease(7.4±2.3) mo] received conventional therapy plus aescine 10 15 mg in 5 % glucose or 0.9 % sodium chloride injection 250 mL,iv,drip,bid,for 7-10 d.Control group of 96 patients[M57,F39;age(42±16)a,course of disease(7±3)mo]only received conventional therapy,including towing,massage,acupuncture,anodyne.Therapeutic effects of both groups were compared after 4 wk.RESULTS:The total effective rate of aescine and control group was 95 % and 81 %,respectively( P <0.05 ),while in those course of disease less than 0.5 a the effective rate was 97 % and 85 %,respectively( P <0.05 ).No obvious adverse reactions occoured. CONCLUSION:Aescine is safe and effective for the treatment of LIDP.The shorter the disease course is,the better the therapeutic effects are.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2001年第3期163-164,共2页
Chinese Journal of New Drugs and Clinical Remedies
