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幽门螺杆菌感染与慢性胃炎红细胞免疫功能变化的关系 被引量:7

The relationship between the infection of Helicobacter pylori and the changes of immunologic function of red blood cells in patients with chronic gastritis
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摘要 目的 :探讨幽门螺杆菌感染与慢性胃炎患者红细胞免疫功能的影响。方法 :采用红细胞C3b受体花环 (RBC -C3bRR)试验、免疫复合物花环 (RBC -ICR)试验、免疫粘附促进因子 (RFER) 百分率及抑制因子 (RFIR)百分率试验 ,检测 3 15例慢性胃炎患者与 3 0例健康体检者红细胞免疫功能情况。结果 :慢性胃炎组RBC -C3bRR、RFER明显低于对照组 (P <0 0 1,P <0 0 5 ) ,RBC -ICR、RFIR高于对照组 ((P <0 0 5 ,P <0 0 1) ;Hp阳性组RBC -C3bRR明显低于Hp阴性组 (P <0 0 5 ) ,RBC -ECR明显高于HP阴性组 (P <0 0 5 ) ,RFER、RFIF两组间比较未见显著差异 ;对 186例Hp阳性根除治疗前、后红细胞免疫功能对比发现治疗后RBC -ICR明显低于根除前 ,其余指标无显著改变。结论 :Hp的感染可能导致宿主红细胞免疫功能紊乱 ,其感染可能是慢性胃炎患者红细胞免疫功能下降的主要原因。 Objective To investigate the changes of immunologic function of red blood cells(RBC)in patients with chronic gastritis infected by helicobacter pylori(HP).Methods The immunologic function of RBC in 315 cases of chronic gastritis was dynamically detected with yeast rosette method before and after treatment.Results The results showed that RBC-C 36 receptor rostte(RBC-C 36RR)rate and RBC immune adherence enhance factor(RFER) rates were lower(P<0.01, P<0.05)and RBC immune complex rosette (RBC-ICR)rate and RBC immune adherence inhibitor factor(RFIR)were higher( P<0.05,P<0.01)in patients with chronic gastritis than those in control group.RBC-C 36RR was obviously lower and PBC-ICR was obviously higher in patients with chronic gastritis infected by HP than those with no HP(P<0.05,P<0.05).There was no great difference in RFER and RFIF between these two groups.RBC-ICR was significantly lower after treatment in 186 patients infected by HP and needing eradication.Conclusions HP infection could reduce immunologic function of RBC in patients with chronic gastritis.
出处 《河南诊断与治疗杂志》 2001年第2期75-77,共3页 Henan Journal of Diagnosis and Therapy
关键词 红细胞免疫 慢性胃炎 幽门螺杆菌 根除术 Erythrocyte immunity Chronic gastritis Helicobacter pylori Eradication
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参考文献8

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二级参考文献3

  • 1郭峰.红细胞增强淋巴细胞与粒细胞免疫粘附肿瘤细胞的作用[J]第二军医大学学报,1989(06). 被引量:1
  • 2郭峰,曹漪明,张延东.系统性红斑狼疮患者的红细胞免疫粘附功能变化[J]上海医学,1987(12). 被引量:1
  • 3徐瑛,郭峰.红细胞对吞噬细胞吞噬功能影响的观察[J]第二军医大学学报,1987(03). 被引量:1

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