摘要
目的 评价姑息切除在中晚期肝癌治疗中的作用。方法 将 1996年 3月～ 2 0 0 0年 1月收治的 98例 (术中证实不能行根治性切除者 )中晚期肝癌患者行癌肿大部分切除加肝动脉置管埋泵化疗等综合治疗 49例 (治疗组 ) ;行肝动脉置管埋泵化疗等综合治疗 49例(对照组 )。结果 治疗组及对照组的AFP下降率分别为 6 0 0 %和 31 7% (P <0 .0 5 ) ;0 5 ,1,3年的生存率分别为 85 7% (4 2 /4 9) ,6 0 5 % (2 3/2 8) ,45 4% (10 /2 2 )和 6 7 3%(33/4 9) ,32 5 % (13/4 0 ) ,10 % (2 /2 0 ) ,(P <0 .0 5 )。
Objective To evaluate the effect of palliative resection of advanced primary hepatocellular carcinoma (PHCC). Methods 98 patients with advanced PHCC were divided randomly into two groups in our hospital from March 1996 to Jan. 2000:(1) Therapy group (49 cases), dealt with palliative resection of liver cancer and implanted with a drug delivery system (DDS). (2) Control group (49 cases), only implanted with DDS. Results In therapy group and control group, The decline rate of AFP was 60.0% and 31.7% respectively (P<0.05); and the survival rates of 0.5, 1, 3 years after operation were 85.7% (42/49), 60.5%(23/38), 45.4%(10/22) and 67.3%(33/49), 32.5%(13/40), 10%(2/20) (P<0.05). Conclusions Palliative resection of liver cancer can improve survival duration and life quality of patients with advanced HCC.
出处
《中国普通外科杂志》
CAS
CSCD
2001年第2期120-122,共3页
China Journal of General Surgery
