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镁盐防治急性心肌梗塞时心律失常的临床研究

The study on the prevention and treatment of arrhythmia of acute myocardial infraction with magnesium sulfate
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摘要 通过对60例AMT患者的临床研究,旨在评价镁盐防治AMI早期心律失常的疗效。治疗组30例患者给予硫酸镁+极化液缓慢静脉滴注,疗程10d;对照组给予极化液。结果表明,缓慢静脉滴注适当剂量和足够疗程的镁盐,才能彻底纠正机体(主要是细胞内)缺镁,从而有效地防治AMI的心律失常。根据镁盐治疗前后血浆、红细胞和尿镁含量,以及∑ST、∑T和心功能的动态变化,对镁盐的作用进行初步探讨。本研究为临床提供了一种有效而且安全治疗AMI的方法。 Sixty patients with AMI were clinically studied to evaluate the effects and methods of preventionand treatment of arrhythmia in the carly period with magnesium sulfate. Intravenous infusion ofmagnesium sulfate plus GIK solution was given slowly to thirty patients. GIK solution was given to thecontrol group. The results showed that slow intravenous infusion of adequate quantity of magnesium for enough time could correct body (mainly intracellular) magnesium deficiency completely, and safelyprevent and treat arrhythmia in AMI. According to the serial changes of the magnesium concentrationsin plasma and erythrocytes,the excretion rate of magnesium in urine and the ∑ST(sum of S--T seg-ments elevation in all the leads), ∑T(sum of inversion depth of T waves in all the leads)and cardiacfunction, preliminary ideas of the magnesium action were discussed. The study provided doctors with aneffective and safe method of treating AMI.
出处 《河南医科大学学报》 1991年第2期128-132,共5页 Journal of Henan Medical University
关键词 镁盐 心肌梗塞 心律失常 magnesium myocardial infarction arrhythmia therapeutics
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