摘要
感染约氏疟原虫之斯氏按蚊,饲以1％二氟甲基鸟氨酸,使卵囊发生退变,第11天电镜下分别观察退变卵囊及对照组正常发育之卵囊外周血细胞之反应。结果表明,对照组中正常发育卵囊之周围无明显血细胞反应。但个别退变卵囊有血细胞趋附;用药组中卵囊均呈不同程度之退变,有的己开始黑化,其周围均有一个或多个血细胞,均属颗粒类细胞。血细胞胞浆内及血细胞与卵囊之间均有许多具微管结构之颗粒,提示卵囊退变后可诱使血细胞趋附,后者并可释放颗粒物质或许还有他种物质,促使包被卵囊和黑化卵囊。
Anopheles Stephensi,infected with Plasmodium yoelii.was fed on 10% sucrose solution containing 1%.difluoromethylornothine(DFMO)to induce the degeneration of its oocysts.On the 11th day after infection,the effects of hemocytes on the normal and degenerated oocysts were observed wtih transmission electron microscopy.In the control group.no hemacytes could be found around the normally-developed oocysts except those degenerated ones.In the DFMO group,all the oocysts underwent degeneration in various degrees and some of them were melanized.All the oocysts were attached by one or more hemocytes which belonged to the category of granulo-cytes morphologically.There were many granules with microtubular construction in the cytoplasm of the hemocytes and in the spaces between a hemocyte and an oocyst.The findings indicate that the degeneration of oocysts can exert a taxic effect on hemocytes and the latter may release the granules and possibly other substances to result in the encapsulation and melanization of the oocysts.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1993年第1期8-10,共3页
Journal of Third Military Medical University
关键词
卵囊
血细胞
黑化
疟原虫病
按蚊属
Plasmodium yoelii
oocyst
Anopheles Stephensi
hemocyte
melanization
difluo-romethylornithine
