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糖尿病酮症酸中毒并发急性胰腺炎26例临床救治分析 被引量:7

Analysis of clinical treatment of 26 cases of diabetic ketoacidosis combined with acute pancreatitis
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摘要 目的:研究糖尿病酮症酸中毒并发急性胰腺炎的临床特点,提高诊治水平。方法:回顾性分析2008-01-2013-12我科收治的糖尿病酮症酸中毒并发急性胰腺炎26例患者的临床资料。结果:26例患者均为青中年,多数(16例)无糖尿病病史,急性起病,腹痛、恶心呕吐、乏力为最常见症状。26例患者入院时血糖明显升高(16.8~36.8mmol/L)、尿酮体强阳性、血PH值降低,26例患者均有血甘油三酯增高(2.2~16.4mmol/L),24例患者血淀粉酶升高达正常值3倍以上,20例患者肾功能受损。26例患者胰腺CT检查均有阳性发现。给予积极治疗后25例患者治愈出院,1例并发多脏器功能障碍综合征死亡。结论:对糖尿病酮症酸中毒出现腹痛的患者应常规检验血淀粉酶,腹痛症状持续存在的患者应行腹部CT检查。早期诊断和早期治疗是提高救治成功率的关键。 Objective:To investigate clinical characteristic of diabetic ketoacidosis combined with acute pancreatitis,which can improve the ability of diagnosis and treatment.Method:Clinical data of 26diabetic ketoacidosis combined with acute pancreatitis patients admitted to our emergency department from January 2008to December2013was investigated in the retrospective study.Result:Selected cases are all young adults and 16patients have no history of diabetes.Acute attack,abdominal pain,nausea,vomiting,fatigue are most common symptoms.All patients are obvious high serum glucose concentrations(16.8~36.8mmol/L),urine ketones,low serum PH and high serum triglycerides(2.2~16.4mmol/L).24patients have three times serum amylase than the normal.20patients combined with kidney injury.All patients have abnormal phenomenon of pancreas with CT examination.25patients are cure with active treatment and one patient die because of multiple organ dysfunction syndromes.Conclusion:Test of serum amylase and triglycerides is important for diabetic ketoacidosis patients with abdominal pain and abdominal CT scan is necessary for continuous abdominal pain patients.Early diagnosis and early treatment is the key for cure.
出处 《临床急诊杂志》 CAS 2014年第6期309-311,共3页 Journal of Clinical Emergency
基金 南京军区重点课题(No:12Z32)
关键词 糖尿病酮症酸中毒 急性胰腺炎 diabetic ketoacidosis acute pancreatitis
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