摘要
通过对上皮间质转化理论基础的回顾,探讨上皮间质转化、间质上皮转化与肝脏纤维化及肝癌干细胞转化的关系,从而寻找肝癌干细胞的相关基因、抗体标记物及关键通路,这不仅有利于肝细胞癌分期的诊断,提示预后,更为寻找医治肝癌的方法提供更多的研究方向。
Through the retrospective analysis of epithelial-mesenchymal transition( EMT),the relationship of epithelial-mesenchymal transition,interstitial epithelial transformation and hepatic fibrosis-renal tubular ectasia syndrome and liver cancer stem cells transition is explored,to find the related gene,antibody markers and the key pathway. This not only does favor on the diagnosis of hepatocellular caricinoma in installment,and does hint on post-diagnosis to find out the research direction of liver cancer diagnosis and treatment.
出处
《黑龙江医学》
2014年第6期617-619,共3页
Heilongjiang Medical Journal
关键词
上皮间质转化
间质上皮转化
肝细胞癌
肿瘤干细胞
微环境
Epithelial-mesenchymal transition
Interstitial epithelial transformation
Hepatocellular carcinoma
Tumor stem cell
Microenvironment