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上皮间质转化与肝癌微环境变化的关系

Relationship Between Epithelial-mesenchymal Transition and Micro-environmental Transition of Hepatocellular Carcinoma
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摘要 通过对上皮间质转化理论基础的回顾,探讨上皮间质转化、间质上皮转化与肝脏纤维化及肝癌干细胞转化的关系,从而寻找肝癌干细胞的相关基因、抗体标记物及关键通路,这不仅有利于肝细胞癌分期的诊断,提示预后,更为寻找医治肝癌的方法提供更多的研究方向。 Through the retrospective analysis of epithelial-mesenchymal transition( EMT),the relationship of epithelial-mesenchymal transition,interstitial epithelial transformation and hepatic fibrosis-renal tubular ectasia syndrome and liver cancer stem cells transition is explored,to find the related gene,antibody markers and the key pathway. This not only does favor on the diagnosis of hepatocellular caricinoma in installment,and does hint on post-diagnosis to find out the research direction of liver cancer diagnosis and treatment.
作者 张勤 张传山
出处 《黑龙江医学》 2014年第6期617-619,共3页 Heilongjiang Medical Journal
关键词 上皮间质转化 间质上皮转化 肝细胞癌 肿瘤干细胞 微环境 Epithelial-mesenchymal transition Interstitial epithelial transformation Hepatocellular carcinoma Tumor stem cell Microenvironment
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