摘要
目的:探讨肺类癌与微瘤型类癌CT表现及病理学特征。方法:(1)采用高压注射器经肘前静脉注射,增强扫描动脉期与静脉期,扫描范围:肺尖到肺底部,包括双侧肾上腺。感兴趣区放置:ROI设定在病灶最大层面,病灶面积70%。(2)术后标本常规石蜡切片HE染色,核分裂计数选取肿瘤生长最活跃区域。免疫组化染色采用EnVision两步法进行。结果:不典型类癌周围型2例,见坏死及肋骨转移1例。典型类癌3例中周围型1例,中央型2例,瘤肺界面均清晰、光滑3例,"冰山征"与"贴边血管征"1例。微瘤型类癌3例CT未见明确瘤灶,均位于肺纤维化背影,镜下小气道附近见瘤细胞巢。8例病灶CK18、CgA、Syn均表达阳性;Ki-67检查4例指数均<5%。结论:肺类癌与微瘤型类癌CT表现与病理特征具相对特征性,认识其特点有助于对分类与临床治疗。
Objective： To explore CT manifestations and pathologic fe atures of pulmonary carcinoid tumours and carcinoid tumourlets. Methods： Retrospective analysis was conducted of the CT imagings and the pathologic features of pulmonary carcinoid tumours （5 cases） and carcinoid tumourlets （3 cases）, which were all diagnosed by pathologic manifes-tations. Results： There were 2 peripheral atypical carcinoid cases in which necrosis and costal metastatic carcinoma were found in 1 case. There were 3 typical carcinoid cases including 2 central types and 1 peripheral type, all of which mani-fested smooth shape and clear boundary with lung tissue in CT imagings and 1 of which showed the ice-berg sign and vas-cular notch symptom. 3 carcinoid tumorlet cases had no characteristics to show definite tumor lesions, pulmonary fibrosis background and tumor cell nests around small airways under the microscope. All 8 cases expressed CK18, CgA and Syn positively and 4 of them had an index lower than 5% by Ki-67 examination. Conclusions： Pulmonary carcinoid tumours and carcinoid tumourlets have their own characteristics relatively in CT and pathologic features.
出处
《交通医学》
2014年第3期221-224,共4页
Medical Journal of Communications
