摘要
目的观察结甲1号方治疗肝郁肾虚型结节性甲状腺肿的临床疗效。方法将88例结节性甲状腺肿患者随机分为对照组和治疗组,每组44例。治疗组予以结甲1号方治疗,对照组予以优甲乐片口服,疗程8周。观察两组临床疗效、证候积分、促甲状腺素(TSH)水平及甲状腺结节大小和数目的变化。结果治疗组总有效率为81.82%,对照组为56.82%;治疗组临床疗效优于对照组(P<0.05)。治疗后两组证候总积分均显著下降(P<0.05),且治疗组积分低于对照组(P<0.05)。两组治疗前后TSH水平比较差异无统计学意义(P>0.05)。两组治疗后甲状腺结节数目减少及最大直径均缩小(P<0.05),且组间有显著性差异(P<0.05)。结论结甲1号方能显著减少肝郁肾虚型结节性甲状腺肿患者结节数目和最大直径,改善临床症状。
Objective To observe the clinical efficacy of ＂Jiejia Formula I＂ in treating nodular goiter （NG） of liver depression and kidney deficiency pattern. Methods Eighty-eight cases with NG were randomized into control group and treatment group, with 44 cases in each group. The treatment group was treated with ＂Jiejia Formula I＂ and control group was treated with Euthyrox Tablets orally, with the course of 8 weeks. The clinical efficacy, symptom score, thyroid stimulating hormone （TSH） level, size and numbers of the thyroid nodules were observed. Results The overall effective rate was 81.82% in the treatment group and 56.82% in the control group, with a difference between the two groups（P 〈 0.05 ）. After treatment, the total symptom score was markedly reduced in both groups （ P 〈 0.05 ） , and the symptom score in treatment group was lower than that of the control group （ P 〈 0.05 ）. No significant difference was found in TSH level between before and after treatment （ P 〉 O. 05 ）. After treatment, the numbers and maximum diameters of the thyroid nodules were reduced in both groups （ P 〈 0.05 ） , with significant difference between the two groups （ P 〈 0.05 ）. Conclusion ＂Jiejia Formula I＂ can reduce the numbers and maximum diameters of the thyroid nodules of liver depression and kidney deficiency pattern and can improve its clinical symptoms.
出处
《上海中医药杂志》
2014年第6期53-54,57,共3页
Shanghai Journal of Traditional Chinese Medicine
关键词
结节性甲状腺肿
结甲1号方
肝郁肾虚型
nodular goiter
＂Jiejia Formula I＂
liver depression and kidney deficiency pattern
