摘要
目的:探讨早发型重度子痫前期期待保守治疗的临床意义,及终止妊娠时机与围生结局的关系。方法回顾性分析2006年10月至2012年8月济南市妇幼保健院收治的293例早发型重度子痫前期患者,分为两组,研究组198例积极治疗,对照组195例期待治疗(入院期待治疗48 h 后终止妊娠),比较两组围生结局。结果研究组终止妊娠孕周数(31.0±0.9)周,新生儿窒息率为60.1%,对照组终止妊娠孕周数(32.0±1.4)周,新生儿窒息率为13.3%,对照组的新生儿窒息率和 NICU 住院率均低于研究组(P 〈0.05),对照组新生儿体质量明显大于研究组(P〈0.01)。结论选择合适的早发型重度子痫前期孕妇进行期待治疗可以明显改善围生儿结局,对孕产妇也是安全和可行的。
Objective To investigate the clinical significance of conservative treatment for the early-onset severe pre-eclampsia,and the relationship between the timing of pregnancy termination and perinatal outcomes. Methods From October 2006 to August 2012,293 cases of early-onset severe pre-eclampsia were divided into two groups,study group(198 cases)received active treatment,control group (195 cases)received the expectant treatment(termination of pregnancy after 48 h of admission to treat-ment),the perinatal outcomes of the two groups ws compared. Results The pregnancy termination of study group was(31. 0 ± 0. 9)w,neonatal asphyxia rate was 60. 1% ,and in control group,the patients terminated pregnancy at(32. 0 ± 1. 4)w,the neonatal asphyxia rate was 13. 3% . The rate of neonatal as-phyxia and NICU of control group was significantly lower than that of study group(P 〈 0. 05),and the neonatal weight of control group was heavier than that of the study group(P 〈 0. 01). Conclusions Ex-pectant treatment can significantly improve the perinatal outcome of pregnant women,and it is safe and feasible for early-onset severe pre-eclampsia.
出处
《中国实用医刊》
2014年第14期7-8,共2页
Chinese Journal of Practical Medicine
关键词
早发型重度子痫前期
期待治疗
围生结局
Early-onset severe pre-eclampsia
Expectant treatment
Perinatal outcome