摘要
目的 探讨低出生体重儿（LBWI）对产妇分娩后高血压患病率的影响.方法 采用回顾性队列研究设计,收集1976年10月至2008年12月间在开滦医疗集团住院分娩且参加2010-2011年度健康体检的3 172例女性资料,根据是否有低体重出生儿史,分为LBWI组与非LBWI组.观察两组的高血压患病情况,采用多因素logistic回归方法分析患高血压的影响因素.结果 3172例女性的平均年龄为42.3岁,其中LBWI组147例,非LBWI组3 025例,所生婴儿平均体重分别为2.31 kg和3.39 kg.LBWI组高血压患者为35例,患病率为23.8％,非LBWI组高血压患者为511例,患病率为16.9％ （P＜ 0.05）.多因素logistic回归分析结果显示,校正分娩年龄、产后血压及查体时BMI、FPG、HDL-C、LDL-C、TC、TG、高敏C反应蛋白后,LBWI组妇女远期发生高血压的风险是非LBWI组的1.60（95％CI：1.02～ 2.53）倍.结论 有LBWI史的妇女分娩后高血压的患病率高于无LBWI史的妇女,即有LBWI史的妇女分娩后患高血压的风险增加.
Objective To compare the prevalence of hypertension between low birth weight infant （LBWI） women and non-LBWI women.Methods A retrospective cohort study was applied and 3 172 pregnant women giving births during October 1976 to December 2008 in our hospital and underwent physical check-up between 2010 and 2011 at the Kailuan medical group were included and divided into LBWI group and non-LBWI group by the history of LBWI.Prevalence of hypertension was obtained during the follow-up program.Multiple logistic regression analysis was used to assess the relative risk of hypertension.Results A total number of 3 172 women,with an average age of 42.3 years old were divided into LBWI group （n=147） and non-LBWI group （n=3 025）,with the average birth weights of their infants were 2.31 kg and 3.39 kg,respectively.The prevalence of hypertension from the follow-up program was significantly higher in LBWI group than that in the non-LBWI group （23.8％ vs.16.9％,P＜0.05）.After adjustment for other traditional risk factors,the risk of hypertension in LBWI group was 1.60（95％CI：1.02-2.53） folds higher than that in the nonLBWI group.Conclusion Prevalence of hypertension in women with LBWI was higher than that in those women without LBWI.History of LBWI seemed to have had an increased risk to develop hypertension.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2014年第7期779-783,共5页
Chinese Journal of Epidemiology
关键词
高血压
低出生体重儿
危险因素
Hypertension
Low birth weight infant
Risk factor
