摘要
合成了形貌具有典型立方晶型结构的404有机担体负载磷钨酸,用这种新型负载型催化剂催化芳香醛与1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮的缩合反应,共合成了6种未见文献报道的吡唑啉酮衍生物,产物通过IR,1HNMR和元素分析表征。研究发现,404有机担体负载磷钨酸催化剂具有稳定的空间结构,分散性好,负载量稳定,对催化此类反应具有催化产率高、催化反应时间短、选择性高、不污染环境和催化剂能够重复利用等特点。
Many loaded-catalysts are applied to the Mannich reaction,but they have disadvantages such as low yield, unsta bility of loaded rate and asking for long time. 404 Organic support loaded phosphotungstic acid was synthesized by the reaction of 404 organic support and phosphotungstic acid in CC14. The effects of different reaction conditions on the yields were investigated. The condensation reaction of aromatic aldehydes and 1-phenyl-3-methyl-4-benzoyl-pyrazolone was catalyzed by 404 organic support loaded phosphotungstic acid. Simultaneously the products were determined by IR, t HNMR and elemental analysis. The catalyst was provided with stable cubic crystal spatial structure and good disper- sion. This protocol has advantages of stability of loaded rate, short time, mild condition, high yield, high selectivity, simple work-up, environmental friendly procedure and the catalyst can be reused.
出处
《化学试剂》
CAS
CSCD
北大核心
2014年第7期646-650,共5页
Chemical Reagents
