摘要
【目的】探讨中青年肥胖男性人群体质量指数（BMI）与各代谢指标的变化。【方法】选取20～52岁男性75例为研究对象。根据BMI分为肥胖组、超重组、对照组三组各25例。对三组的代谢指标及人体基本参数进行检测及比较。【结果】三组比较，中青年男性肥胖组收缩压（SBP）、舒张压（DBP）、总胆固醇（TC）、三酰甘油（TG）、血尿酸（UA）、睾酮（T）、餐后2 h血糖（2 hPG）、空腹胰岛素（FINS）、餐后2 h胰岛素（2 hINS）、胰岛素抵抗指数（HOMA-IR）差异有统计学意义（分别为P ＜0．01或P ＜0．05）；HDL-C、LDL-C、FPG比较无统计学意义（P≥0．05）。多元线性回归分析最终进入回归方程的因素有 SBP、TC、T和 FINS。【结论】早期干预导致BMI增加的相关代谢因素以预防代谢综合征及相关疾病的发生发展有重要意义。
[Objective]To explore the changes of body mass index（BMI）and metabolic indexes in obese young and middle-aged men.[Methods]Totally 75 men aged 20~52 years old were chosen.According to BMI,all subjects were divided into obese group（n=25）,overweight group（n=25）and control group（n=25）.Metabolic indexes and basic human body parameters among 3 groups were measured and compared.[Results]There were significant difference in systolic blood pressure（SBP）,diastolic blood pressure（DBP）, total cholesterol（TC）,triglyceride（TG）,uric acid（UA）,T,2 HPG,FINS,2 HINS and HOMA-IR among 3 groups（P〈0.01 orP〈0.05,respectively）.There was no significant difference in HDL-C,LDL-C and FPG among 3 groups（P≥0.05）.The factors of multiple linear regression analysis finally entering the regression e-quation were SBP,TC,T and FINS.[Conclusion]The related metabolic factors of early intervention leading to weight gain has the important significance in preventing the occurrence and development of metabolic syn-drome and the related diseases.
出处
《医学临床研究》
CAS
2014年第5期900-902,共3页
Journal of Clinical Research
