摘要
目的：研究不同雌激素受体亚型（ERα，ERβ）在绝经后子宫内膜息肉中的表达及临床意义。方法：采用免疫组化方法对绝经后正常子宫内膜和子宫内膜息内中雌激素受体α和β进行叫定。结粜：免疫组化方法硷删ERα、ERβ在以上两组的阳性率，提示ERα在绝经后子宫内膜息内中呈高表达，ERβ在正常绝经后子宫内膜及子宫内膜息肉中均呈低表达。结论：绝经后局部雌激素受体表达失衡，尤其是ERα高表达，是造成子宫内膜息肉的重要原因之一。
Objectives：To study the expression of different subtype of Estrogen Receptor in postmenopausal endometrium and postmenopausal endometrial polyps. Methods ：Immunohis- tochemical method was used to detect the expressions of ERα and ERβin endometrial polyps tissue and endometrium tissue of post-menopausal women. Results The expression of ERa showed significant higher in postmenopausal endometrial polyps. Conclusions： The high expression of ERαmaybe has great relationship with endometrial polyp＇s formation.
出处
《药物与人》
2014年第7期96-96,共1页
Medicine & People
关键词
子宫内膜息肉
雌激素受体亚型
绝经后
Endometrial polyps
Subtype of Estrogen Receptor
Postmenopausal
