摘要
目的:了解2011—2013年湖南省江永县人民医院住院患者药品不良反应(ADR)发生情况,分析原因,以提高ADR监测工作质量,促进临床合理用药。方法:对2011—2013年住院部收集到的153份ADR报告,分别从患者的年龄、性别、ADR涉及的药品情况、累及器官或系统及其临床表现、给药途径、ADR的类型情况等方面进行回顾性统计分析。结果:153例ADR报告中,60岁以上老年患者更容易发生ADR(占37.25%);引发ADR的给药途径中,以静脉给药为主(占90.20%);所涉及的药品中,抗感染药物居首位(占41.83%);发生ADR的临床表现以皮肤及附件损害最为常见(占39.05%);合用药品种类越多,不良反应发生率越高。结论 :临床应加强用药监护,进一步加强ADR的监测和宣传工作,提高医务人员责任意识,减少ADR的重复发生,确保临床用药安全。
OBJECTIVE：To investigate the adverse drug reactions （ADRs） occurred among the inpatients in Hunan Jiangyong County People＇s Hospital during 2011-2013 period and analyze their causes in order to improve the quality of ADR monitoring and promote rational use of drugs.METHODS：A total of 153 ADR cases collected in the inpatient department of our hospital during 2011-2013 period were respectively and statistically analyzed with regard to patient＇s age and genger,ADR-involved drugs,organs or systems involved,clinical manifestation,route of administration and ADR types,etc.RESULTS：Of the 153 ADR cases,patients aged above 60 years took the lead （accounting for 37.25%）; regarding the route of administration,intravenous administration took the lead （accounting for 90.20%） ; of all the drugs involved,the anti-infection drugs dominated the first place （accounting for 41.83%） ; the ADRs manifested mainly as lesions of skin and its appendants （accounting for 39.05%）.The more drugs used in combination,the higher was the incidence of adverse reactions.CONCLUSIONS：It is important to strengthen medication monitoring clinically as well as ADR monitoring,raise medical personnel＇s awareness of the responsibility,reduce repeated occurrence of ADR and ensure the clinical medication safety.
出处
《中国医院用药评价与分析》
2014年第5期454-458,共5页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
分析
合理用药
Adverse drug reaction
Analysis
Rational use of drug
