摘要
目的:研究剖宫产麻醉中运用浓度不等的罗哌卡因与地卡因的临床效果。方法:我院选择2010年3月-2012年3月间进行剖宫产手术的300例产妇,将其随机分为三组,患者均采用腰硬联合麻醉,一组运用0.75%的罗派拉因等比重液,二组运用0.5%罗派卡因等比重液,三组用0.33%地卡因等比重液,所有药物均通过蛛网膜下腔给药。结果:前两组产妇的药物起效时间以及运动恢复时间未见明显差异,无统计学意义(P>0.05),但是两组与第三组比较,差异较为显著(P<0.05)。第一、三两组的临床麻醉效果基本一致,无统计学意义(P>0.05),但是与第二组比较,差异显著P<0.05)。术中第一、二两组患者的恶心、呕吐几率显著低于三组(P<0.05);所有患者术后均未见明显神经系统及头痛等并发症。结论:地卡因及罗哌卡因都可以满足剖腹产的需要,但是相对来说,后者对血流动力学的影响较小,对患者来说更加安全有效。
Objective：To explore the clinical effects of different concentrations of equivalent dose of ropivacaine and dicaine in the application of anesthesia in cesarean section. Methods：300 pregnant women undergoing cesarean section from March 2010 to March 2012 were selected, and were randomly divided into 3 groups. Group 1 was given 0.75%ropivacaine of equivalent dose, group 2 was given 0.5%ropivacaine of equivalent dose, and group 3 was given 0.33%dicaine of equivalent dose. All cases were given spinal-epidural anesthesia, and all drugs were given through subarachnoid space. Results：There was no statistical difference on drug＇s onset time and motion recovery time in group 1 and 2 （P〉0.05）, yet there was statistical difference on them between group 1 and 2 with group 3（P〈0.05）. Group 1 and 3 had similar anesthesia effect（P〉0.05）, yet there was statistical difference on them comparing with group 3（P〈0.05）. During operation, group 1 and 2＇s rates of nausea and vomit was lower than that in group 3（P〈0.05）. There was no obvious nervous system, headache and other complications in all cases after operation. Conclusion：Dicaine and ropivacaine both can meet caesarean section＇s need, yet ropivacaine has less influence on hemodynamics, so it has higher safety and effect.
出处
《中国医药导刊》
2014年第5期836-836,838,共2页
Chinese Journal of Medicinal Guide
关键词
罗哌卡因
地卡因
不同浓度
等效剂量
剖宫产
Ropivacaine
Dicaine
Different concentrations
Equivalent dose
Cesarean section
