摘要
目的探讨序贯应用硝普钠与硝酸甘油治疗急性左心衰竭的临床疗效。方法将67例急性左心衰竭患者随机分为观察组34例及对照组33例,均予综合基础治疗,同时对照组给予硝普钠治疗,观察组给予硝普钠治疗后及时换用硝酸甘油治疗,对比2组疗效及不良反应。结果 2组治疗后均能有效改善血压、心功能,2组间心功能改善方面比较差异无统计学意义(P>0.05);观察组不良反应发生率显著低于对照组(P<0.05)。结论在抢救急性左心衰竭过程中,序贯应用硝普钠与硝酸甘油与单一应用硝普钠有同样的治疗效果,且不良反应更少。
Objective To investigate the effects of sequential application of sodium nitroprusside and nitroglycerin in the treatment for acute left heart failure. Methods Sixty-seven patients with acute left ventrieular failure were randomly divided into the observation group and the control group. The control group received the treatment of sodium nitroprusside, and the observation group received the combination treatment of nitroglycerin and sodium nitroprusside on the base of basic therapy. Results After treatment, the blood pressure, heart function were significantly improved （P〈0. 05）. There was no significant difference in cardiac function between the two groups. The incidence rate of side reactions in the observation group Was lower than that in the control group. Conclusions In acute left heart failure patients, the sequential application of sodium nitroprusside and nitroglycerin could improve the blood pressure and heart function, with less adverse reaction.
出处
《实用老年医学》
CAS
2014年第6期491-492,496,共3页
Practical Geriatrics
关键词
硝酸甘油
硝普钠
急性左心衰竭
nitroglycerin
sodium nitroprusside
acute left heart failure
