摘要
目的探讨和研究产后抗支原体治疗对产科切口感染的影响及安全性。方法选取产后(剖宫产或阴道分娩)有切口且孕期生殖道支原体检查阳性的产妇120例为研究对象,采取数字标记法将其分成对照组和治疗组,每组各60例。治疗组产后依据药敏试验行抗支原体治疗,对照组不给予抗支原体治疗,观察两组产妇的产后切口感染率及不良反应发生率。结果治疗组的切口感染率为1.67%,对照组为15.00%,治疗组的切口感染率明显低于对照组(P<0.05);两组的不良反应发生率差异无统计学意义(P>0.05);治疗组的切口愈合时间为(12.6±4.2)d,住院时间为(16.9±5.1)d,均明显短于对照组的(18.5±5.4)、(22.6±4.9)d(P<0.05)。结论临床上对产后有切口且孕期生殖道支原体检查阳性的产妇,预先给予药敏试验后,行针对性抗支原体治疗,能有效降低其产后切口感染率,这对缩短产妇的住院时间,提升其生活质量有积极的意义,此预防性应用抗生素治疗是必要的,可作为临床指导抗生素使用的依据。
Objective To explore and study the influence of anti-Mycoplasma therapy of postpartum on incision infec-tion and its safety. Methods 120 puerperae （cesarean section or vaginal delivery） with postpartum incision and the pos-itive genital tract Mycoplasma examination during pregnancy were selected as subjects,and they were divided into the control group （n=60） and the treatment group （n=60） by taking digital notation, the treatment group was given anti-My-coplasma treatment according to drug sensitive test,the control group was not given anti-Mycoplasma treatment,incision infection rate and the incidence rate of adverse reaction of the two groups were compared. Results Incision infection rate of the treatment group was 1.67%,while the control group was 15.0%,incision infection rate of the treatment group was obviously than that in the control group （P〈0.05）;there was no statistical difference of adverse reaction in the two groups （P〉0.05）;incision healing time of the treatment group[ （12.6±4.2） d ]and hospital stay[ （16.9±5.1） d] were both shorter than those of the control group [（18.5±5.4）,（22.6±4.9） d respectively] （P〈0.05）. Conclusion Puerperae （cesarean section or vaginal delivery） with postpartum incision and the positive genital tract Mycoplasma examination during pregnancy given the targeted anti-Mycoplasma treatment according to drug sensitive test can effectively reduce postpar-tum incision infection rate,and it has a positive significance for shortening hospital stay,and improve quality of life,the prophylactic use of antibiotics is necessary,it can be used as a basis for the use of clinical antibiotic.
出处
《中国当代医药》
2014年第18期21-23,共3页
China Modern Medicine
基金
广东省深圳市龙岗区科技发展资金医疗卫生项目(ys2012060)
关键词
支原体感染
产后
抗生素预防
Mycoplasma infection
postpartum
Antibiotic prophylaxis
