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皮肤细胞性纤维组织细胞瘤临床病理特征

The clinical and pathological features of skin cellular fibrous histiocytoma
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摘要 目的 探讨皮肤细胞性纤维组织细胞瘤(cFH)的临床和病理特征.方法 对7例cFH的临床资料、病理组织形态和免疫组化进行研究,并文献复习.结果 7例原诊断的cFH,6例维持原诊断.6例cFH中男4例,女2例,年龄23~43岁;发生于上臂3例,大腿1例,肩部1例,足部1例,病程为5个月~1年;均有经典型皮肤纤维瘤的组织学特征,最大的特征是出现高度致密的梭形细胞或卵圆形细胞.结论 cFH临床复发率高,少数病例可发生区域淋巴结或肺转移;在临床病理诊断中容易与隆突性皮肤纤维肉瘤造成混淆. Objective To investigate the clinical and pathological features of skin cellular fibrous histiocytoma (cFH). Methods 7 cases primarily diagnosed as cFH were studied by clinical data analyses,pathological histology and immunochemistryl, and the literatures were reviewed. Results Among 7 cases, 6 cases were correct. Among 6 cases of cFH ,4 cases were males and 2 cases were females, age ranging from 23 to 43 years.Tumors arose on the upper arm in 5 patients, thigh in 1, shoulder in 1, foot in 1.The duration ranging from 5 months to 1 year.All 6 cases of cFH showed histologie features of classical dermatofibroma.The biggest feature was the emergence of highly dense spindle cell or ovoid cells. Conclusion The recurrence rate of cFH is high,and a few cases metastasizing to regional lymph nodes or lungs have been reported. In clinical diagnosis of pathology, cFH is easy to confuse with dermatofibrosarcoma protuberans.
出处 《中国现代医生》 2014年第19期85-87,F0003,共4页 China Modern Doctor
关键词 细胞性纤维组织细胞瘤 临床病理 隆突性皮肤纤维肉瘤 鉴别诊断 Cellular fibrous histiocytoma Clinical and pathological Dermatofibrosarcoma protuberans Differential diagnosis
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