摘要
目的探讨糖尿病患者合并干眼症的发生情况及其与血糖水平的关系,为临床预防及治疗糖尿病合并干眼症提供参考。方法回顾性分析2011年7月至2013年7月来该院就诊的糖尿病合并干眼症患者60例(实验组),同时选取60例健康者(健康对照组),比较2组研究对象基础泪液分泌值、泪膜破裂时间以及角膜荧光素染色评分,并分析糖尿病患者此3项指标与血糖水平的关系。结果实验组患者基础泪液分泌值为(6.85±3.76)mm、泪膜破裂时间(4.39±2.17)s均低于健康对照组,角膜荧光素染色评分(1.86±0.98)分高于健康对照组,2组比较差异均有统计学意义(P<0.05);患者基础泪液分泌值、泪膜破裂时间与血糖水平呈负相关(r=-0.311、-0.419),角膜荧光素染色评分与血糖水平呈正相关(r=0.387,P<0.05)。结论糖尿病患者的基础泪液分泌值、泪膜破裂时间较健康者明显降低,而角膜荧光素染色评分却明显增高,控制患者血糖水平对改善患者干眼症状具有重要临床意义。
Objective To investigate the incidence of diabetic patients with xerophthalmia syndrome and its re-lationship with blood glucose levels ,and to provide reference for clinical prevention and treatment on diabetes with xerophthalmia reference .Methods 60 cases of diabetic patients with xerophthalmia had a retrospective analysis from July 2011 to July 2013 in our hospital ,while 60 healthy people were selected as the control group ,schirmer values , tear breakup time and corneal fluorescein staining score were compared analysis beteen the two groups ,and the rela-tionship between the this three indicators and the blood glucose levels were analysised on the diabetic patients with xerophthalmia .Results In diabetic group ,the schirmer values was （6 .85 ＆#177; 3 .76）mm ,tear film break-up time was （4 .39 ＆#177; 2 .17） s ,which were all lower than the control group ,corneal fluorescein staining score was （1 .86 ＆#177; 0 .98） points which was higher than the control grouop ,the difference were all statistically significant （P〈0 .05） .In diabetic group ,schirmer values ,tear breakup time had negatively correlative with blood glucose levels （r= -0 .311 ,-0 .419） , corneal fluorescein staining score hadpositively correlative with blood glucose levels （r=0 .387 ,P〈0 .05） .Conclusion Diabetic patients have a lower schirmer values and tear breakup time ,have a higher fluorescein staining score .It has clinical value by controling the blood sugar levels on patients with xerophthalmia symptoms .
出处
《检验医学与临床》
CAS
2014年第12期1653-1654,共2页
Laboratory Medicine and Clinic
关键词
糖尿病
干眼症
血糖
相关性分析
diabetes mellitus
xerophthalmia
blood sugar
correlation analysis
