摘要目的观察经皮冠状动脉(冠脉)介入治疗高龄冠心病(C A D)患者的效果。方法老年C A D患者1 2 0例作为观察组,同期的青中年C A D患者1 2 0例作为对照组,两组均经冠脉造影确诊,接受经皮冠脉介入治疗,随访6个月。结果观察组的冠脉病变以多支为主,冠脉狭窄程度高,对照组以单支为主;两组差异有统计学意义。观察组血管直径略小于对照组,支架植入率、植入成功率、并发症发生率、再住院率及病死率两组接近,差异均无统计学意义。结论经皮冠脉介入治疗老年C A D安全可靠,治疗效果佳,并发症少。
3Sakamoto T,Nakao K,Ogawa H.Calcium channel antagonists prevent cardiovascular events in Japanese patients with myocardial infarction even in the absence of coronary artery spasm[J].Circ J,2011,75(7):1577. 被引量:1
4Resnic FS,Wainstein M,Lee MK,et al.No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention[J].Am heart J,2003,145:42. 被引量:1
5Topol EJ,Yadav JS.Recognition of the importance of embolization in atherosclerotic vascular disease[J].Circulation,2000,101:570. 被引量:1
6ZHOU Z, LIU Y, MIAOA D, et al. Protoeatechuic aldehyde suppresses TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells[J]. Eur J Pharmacol,2005,513:1-8. 被引量:1
7STEINBERG H O, PARADISI G, HOOK G, et al. Free fatty acid elevation Impairs insulin mediated vasodilation and nitric oxide production[J]. Diabetes, 2000,49 : 1231-1238. 被引量:1
8ZHOU Y T, GRAYBURN P, KARIM A, et al. Lipotoxic heart disease in obese rats: implications for human obesity[J]. Proc Natl Acad Sci USA, 2000, 97:1748--1789. 被引量:1
9SIMOPOULOS A P. The importance of the omega-6/ omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases[J].Exp Biol Med(Maywood), 2008,233:674-688. 被引量:1
10RHEE Y, PAIK M J, KIM K R. Plasma free fatty acid level patterns according to cardiovascular risk sta- tus in postmenopausal women[J]. Clin Chim Acta, 2008,392:11-16. 被引量:1