摘要
[目的]观察天麻熄风汤联合尼莫地平防治蛛网膜下腔出血后迟发性脑血管痉挛的疗效。[方法]选取2009年6月至2013年6月间在本院和浙江大学附属第二医院住院治疗的64例蛛网膜下腔出血患者,随机分为试验组和对照组,每组32例。对照组患者静脉滴注尼莫地平,试验组患者在对照组的基础上加服天麻熄风汤加减。对比分析两组患者迟发性脑血管痉挛和脑梗死的发生率,以及经颅多普勒超声(TCD)检测结果。[结果]试验组患者血管痉挛的总发生率低于对照组,差异有统计学意义(P<0.01);试验组患者脑梗死发生率低于对照组,差异有统计学意义(P<0.01)。两组患者治疗前两侧大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)的血管收缩峰流速(Vp)值间差异均无统计学意义(P>0.05)。治疗后试验组患者两侧ACA、MCA的Vp值与对照组相比明显减慢,差异有统计学意义(P<0.05)。[结论]天麻熄风汤联合尼莫地平能有效降低蛛网膜下腔出血后迟发性脑血管痉挛和脑梗死的发生,改善预后。
Objective] To investigate the Gastrodia elata Xifeng decoction combined with nimodipine in the treatment of subarachnoid hemorrhage of delayed cerebral vasospasm after effect.[Method] 64 subarachnoid hemorrhage patients from June 2011 to June 2012 in our hospital,were randomly divided into experimental group and control group,each group of 32 cases.Patients in the control group with intravenous nimodipine,patients in the experimental group on the basis of clothing Gastrodia Xifeng decoction.Comparative analysis of two groups of patients incidence of delayed cerebral vasospasm and cerebral infarction.[Result] In the experimental group,the incidence of vasospasm in patients compared with the control group had significant difference;the incidence of cerebral infarction patients in the experimental group compared with the control group had significant difference too（P 〈0.01）.[Conclusion] Gastrodin Xifeng decoction combined with nimodipine can effectively reduce the subarachnoid hemorrhage cerebral vasospasm and cerebral infarction,and improve the prognosis.
出处
《浙江中医药大学学报》
CAS
2014年第5期587-589,共3页
Journal of Zhejiang Chinese Medical University
关键词
天麻熄风汤
尼莫地平
蛛网膜下腔出血
迟发性脑血管痉挛
脑梗死
Gastrodia elata Xifeng Decoction
Nimodipine
subarachnoid hemorrhage
delayed cerebral vasospasm
cerebral infarction
