摘要
目的了解广州市孕产妇艾滋病病毒(HIV)感染的特征及母婴阻断情况,为进一步做好艾滋病母婴阻断提供依据。方法 2009年10月至2010年9月,对接受婚检、产检及助产服务的孕产妇进行HIV筛查,阳性个案进行确诊试验。对HIV感染孕产妇及其新生儿的一般情况、干预效果进行分析。结果广州市全人口孕产妇HIV抗体阳性检出率为0.02%(41/178 029)。HIV感染孕产妇平均年龄27岁,绝大多数为汉族,受教育程度偏低,大部分无业或农民;最可能的感染途径是性传播。76.9%(30/39,2例失访)的孕产妇顺利分娩;分娩产妇中母亲用药率为56.7%(17/30),婴儿用药率为60.0%(18/30);46.7%(14/30)的婴儿成功随访至结案,未检出HIV感染个案。结论母婴阻断效果明显。在母婴阻断干预过程中,HIV感染孕产妇及其婴儿的随访工作难度较大,要根据孕产妇人群的特点有针对性地开展工作。
Objective To investigate the epidemiologic features of maternal human immunodeficiency virus （HIV） infection and prevention of mother-to-child transmission （PMTCT） in Guangzhou , and provide evidence for further work of PMTCT. Methods The women undergoing premarital medical examination, prenatal medical check and institutional delivery were given HIV antibody screening test from October, 2009 to September, 2010. Confirm- atory test was given when screening test was positive. Effects of PMTCT and general condition of HIV-infected pregnant women and their babies were analyzed. Results The detectable rate of HIV infection among pregnant women in Guangzhou was 2.30 per 10,000 people （41/178029）. The average age of HIV-infeeted pregnant women was 27 years old. Most infected people had a nationality of Han and a low education level. The most common occupation type was unemployment and farmer. The most likely route of infection was sexual transmission. Among the infected women, 76.9% （30/39, 2 cases lost of follow-up） delivered smoothly, with 56.7% （17/30） using antiretroviral drugs. Among their babies, 60. 0% （18/30）used antiretroviral drugs, and 46.7 % （14/30）were followed up to 18 months with no HIV positive cases. Conclusion The PMTCT of HIV is effective. Due to the difficulty of HIV- infected pregnant women and their babies, it is imperative to provide integrated MTCT prevention service according to the features of different populations.
出处
《中国艾滋病性病》
CAS
2014年第5期340-342,共3页
Chinese Journal of Aids & STD
