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坤泰胶囊治疗特发性卵巢早衰疗效观察 被引量:14

Clinical observation of “Kuntai Capsule” for the treatment of idiopathic premature ovarian failure
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摘要 目的观察坤泰胶囊治疗特发性卵巢早衰的临床疗效。方法将60例特发性卵巢早衰患者随机分为两组,各30例;治疗组给予坤泰胶囊联合周期性激素替代治疗,对照组给予周期性激素替代治疗,疗程3个月。结果治疗3个月后两组临床疗效无显著性差异(P>0.05);6个月后随访,治疗组复发率为16.67%,对照组为63.33%;治疗组复发率低于对照组(P<0.01)。治疗后两组血清FSH和LH水平明显降低(P<0.01),E2水平升高(P<0.01);两组E2、FSH、LH水平比较差异有统计学意义(P<0.01)。结论坤泰胶囊可改善特发性卵巢早衰患者的卵巢功能。 Objective To observe the clinical efficacy of "Kuntai Capsule" in treating idiopathic premature ovarian failure (POF). Methods Sixty cases with POF were randomized into two groups: treatment group in which 30 cases were treated by '" Kuntai Capsule" and periodical hormone replacement therapy ( HRT), and control group in which 30 cases were treated by periodical HRT, with the course of 3 months. Results After 3 months treatment, no significant difference was found in clinical efficacy between the two groups ( P 〉 0. 05 ) ; 'after 6 months follow - up, the recurrence rate was 16.67% in the treatment group and 63.33 % in the control group, with significant difference between the two groups (P 〈0.01 ). After treatment, the levels of serum FSH and LH were reduced (P 〈 0.01 ), the E2 level was increased in both groups ( P 〈 0.01 ) ; there were significant differences in the levels of E2, FSH, LH in both groups ( P 〈 0.01 ). Conclusion "Kuntai Capsule" can improve the ovarian function in patients with idiopathic POF.
作者 苏爱芳 南燕
出处 《上海中医药杂志》 2014年第5期79-80,共2页 Shanghai Journal of Traditional Chinese Medicine
关键词 坤泰胶囊 特发性卵巢早衰 激素替代疗法 " Kuntai Capsule" idiopathic premature ovarian failure hormone replacement therapy (HRT)
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  • 1谢幸.妇产科学[M].北京:人民卫生出版社,2013:274. 被引量:385
  • 2覃春容,姚吉龙,朱文杰,唐雪莲,任晓慧.特发性卵巢早衰发病相关因素分析[J].实用妇产科杂志,2013,29(2):133-136. 被引量:28
  • 3Qin CR, Chen SL, Yao .JL, et al. Identification of two novel missense mutations of TGFBR3 gene in Chinese women with idiopathic prenmture ovarian failure [ J ]. Reprod Biomed Online, 2011,23 ( 6 ) : 697- 703. 被引量:1
  • 4Qin CR, Yao JL, Zhu WJ, et al. FOXE1 polyalanine tract length screening by MLPA in idiopathic premature ovarian failure[ J ]. Reprod Biol Endocrinol, 2011, 9 ( 1 ) : 158-160. 被引量:1
  • 5吴洁,周重宛.卵巢早衰31例临床分析及治疗探讨[J].南京医科大学学报(自然科学版),2005,25(1):44-46. 被引量:10
  • 6马良坤,林守清.卵巢早衰与卵巢不敏感综合征[J].实用妇产科杂志,2003,19(4):198-200. 被引量:98
  • 7罗萍.坤泰胶囊治疗更年期综合征87例临床观察[J].中医杂志,2002,43(Suppl):258. 被引量:3
  • 8张毅,盂庆伟,李江红.坤泰胶囊治疗更年期综合征的临床疗效观察[J].中医杂志,2002,43(Suppl):264. 被引量:2
  • 9张绍芬,朱慧庭,刘呖,等.坤泰胶囊对更年期大鼠卵巢功能及子宫内膜影响的实验研究[J].中华老年杂志,2004,23(9):648. 被引量:4

二级参考文献19

  • 1Van Kasteren YM, Schoemaker J. Premature ovarian failure: a systematic review on therapeutic interventions to restore ovarian function and achieve pregnancy. Hum-Reprod-Update, 1999 Sep-Oct,5(5) : 483-492. 被引量:1
  • 2Arici A, Matalliotakis IM, Koumantakis GE et al. Diagnostic role of inhibin B in resistant ovary syndrome associated with secondary amenorrhea. Fertil Steril,2002, 78(6): 1324-6. 被引量:1
  • 3Laml T, Schulz-Lobmeyr I, Obruca A, et al. Premature ovarian failure: etiology and prospects [J]. Gynecol Endocrinol, 2000,14:292-302. 被引量:1
  • 4Check JH, Preut TE, Herbst AL, et al. Pregnancy in premature ovarian failure after therapy with oral contraceptives despite resistance to previous human menopausal gonadotropin therapy [J]. Am J Obstet Gynecol, 1989,160:114-119. 被引量:1
  • 5Chattopadhyay D, Sen MR, Katigar P, et al. Antiovarian antibody in premature ovarian failure [J]. Indian J Med Sci, 1999,53:254-258. 被引量:1
  • 6Holland C. 47 Xxx adolescents with POF and autoimmune disease[J]. J Pedia Adolesc Gynecol, 2000,13:93-95. 被引量:1
  • 7Kalantaridou SN, Davis SR, Nelson LM, et al. Premature ovarian failure[J]. Endocrinology and Metabolism Clinics of North America, 1998,27:989-1006. 被引量:1
  • 8Conway GS. Premature ovarian failure [J]. Br Med Bull, 2000,56: 643-649. 被引量:1
  • 9Anasti JN. Premature ovarian failure: an update[J]. Fertil Steril, 1998,70:1-15. 被引量:1
  • 10Mainini G, Festa B, Messalli EM, et al. Premature ovarian failure clinical evaluation of 32 cases [J]. Minerval Ginecol, 2003,55:525-529. 被引量:1

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