摘要
目的:探讨经肝动脉插管化疗栓塞术(TACE)和γ射线立体定向放射(γ刀)在不同时序上介入对原发性肝癌的疗效。方法:将53例原发性肝癌患者分为A、B两组,A组先行TACE后行γ刀治疗,B组先行γ刀后行TACE治疗,对照分析两组在疗效、生存期、复发时间、不良反应等方面的差异。结果:两组有效率分别为77.4%和77.3%,随访6、12、18个月,生存率分别为96.8%、80.6%、77.4%和63.6%、45.5%、18.2%。复发率分别为0%、16.1%、35.5%和18.2%、40.9%、77.3%。不良反应相似。结论:两组在有效率方面无差异,但在生存期和复发时间方面A组明显优于B组,而不良反应相似,表明不同方法在不同时序上介入对原发性肝癌治疗结果有直接影响。
Objective：To investigate the difference in the efficacy of transcatheter arterial chemoembolization（ TA-CE）and gamma ray stereotactic radiotherapy（γknives）in different timing for primary liver cancer. Methods：All 53 patients with primary liver cancer were divided into two groups,patients in group A was treated with TACE and then with gamma knife,patients in group B was treated with gamma knife and then with TACE. To compare the efficacy, survival,recurrence time,adverse reaction between the two groups. Results：The efficacy were 77. 4% and 77. 3% in two groups,and after 6,12,and 18 months of follow-up,survival rates were 96. 8%,80. 6%,77. 4% and 63. 6%, 45. 5%,18. 2%,and recurrence rates were 0%,16. 1%,35. 5% and 18. 2%,40. 9%,77. 3%,and had similar ad-verse reactions. Conclusion：The treatment in two groups had no significant difference in efficacy,but the survival and recurrence time in group A was significantly better than group B,and had similar adverse reactions,indicated that the different timing of interventional treatment for primary liver cancer had directly impact on treatment outcomes.
出处
《现代肿瘤医学》
CAS
2014年第6期1372-1374,共3页
Journal of Modern Oncology
关键词
原发性肝癌
经肝动脉插管化疗栓塞术
γ射线立体定向放射
时序
primary liver cancer
transcatheter arterial chemoembolization
gamma ray stereotactic radiotherapy
tim-ing
