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2013年美国血液学会年会:多发性骨髓瘤的研究进展 被引量:6

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摘要 2013年美国血液学会(ASH)年会发布了多发性骨髓瘤(MM)最新临床研究成果,如用于MM的微小残留病(MRD)检测的流式细胞术(FCM)、聚合酶链式反应(PCR)技术、血清重轻链(HLC)检测及正电子发射计算机断层X线体层成像技术(PET/CT)等新型检测技术.根据MM瘤细胞的遗传学异常进行危险度分层,可针对不同患者制定合理的个体化治疗方案,使患者获得最佳缓解疗效.来那度胺、硼替佐米、卡非佐米等新型药物的应用,可显著提高MM患者的缓解率;应用序贯自体造血干细胞移植(AHSCT)与异基因造血干细胞移植(allo-HSCT),可改善MM患者的生存质量.笔者拟就本次年会关注的有关MM监测、危险度分层、治疗新药及造血干细胞移植(HSCT)的研究进展进行综述.
出处 《国际输血及血液学杂志》 CAS 2014年第3期229-234,共6页 International Journal of Blood Transfusion and Hematology
基金 国家自然科学基金(81172252) 首都临床特色应用研究专项资助课题(Z131107002213146)
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