摘要
目的比较七氟醚和瑞芬太尼麻醉用于声带息肉摘除手术中血压和心率的变化。方法选择2012年2月~2014年2月山东省烟台市北海医院ASAⅠ~Ⅱ级、择期行声带息肉摘除术患者100例,随机分为两组:七氟醚吸入麻醉组(简称A组)和瑞芬太尼静脉麻醉组(简称B组)。七氟醚组给予吸入七氟醚,浓度为4%~6%;瑞芬太尼组持续泵注瑞芬太尼20~40μg/kg,入室至麻醉苏醒期间连续观察SBP、DBP、HR、SpO2,记录停药至苏醒时间及苏醒质量,记录患者苏醒期并发症的发生数。结果在气管插管时B组HR、SBP、DBP均高于A组(P<0.05),同时B组的HR、SBP均高于基础值(P<0.05);支撑喉镜植入后1 min时B组的HR、SBP、DBP明显低于A组(P<0.05),A组的SBP、DBP明显高于基础值(P<0.05)。结论瑞芬太尼和七氟醚均可用于声带息肉摘除术中的麻醉,但是七氟醚对循环系统尤其对心率的干扰较小,可安全有效地用于该类手术的麻醉。
Objective To compare changes of sevoflurane and remifentanil anesthesia in glottic polypus removal surgery in blood pressure and heart rate.Methods From February 2012 to February 2014 in Yantai Beihai Hospital, 100 patients （ASA I^II） scheduled for polyp of vocal cord removal were randomly allocated to two groups. Group A were given anesthetic maintenance with 4%~6%; while group B were given anesthetic maintenance with continuous infusion of remifentanil 20~40μg/kg instead. Continuously observe SBP, DBP, HR, SpO2 from entering operation room. Record the time from drug withdrawal to palinesthesia and quality of palinesthesia.Results HR, SBP, DBP were significantly higher in group B than that in group A while tracheal intubation （P〈0.05, compared with group A）; at the same time, HR, SBP in B group were higher than that of base value（P〈0.05, compared with base value）. HR, SBP, DBP were significantly lower while insertion laryngoscope in group B than those in group A（P〈0.05, compared with group B）. SBP, DBP in group A were significantly higher than that in basal value（P〈0.05, compared with base value）.Conclusion Remifentanil and sevoflurane can be used for anesthesia in vocal cord polyp, but the sevoflurane on circulatory system, especially on heart rate smaller interference, it can be used safely and effectively in the anesthesia of vocal cord polyp.
出处
《中国实用医药》
2014年第13期3-5,共3页
China Practical Medicine
关键词
七氟醚
瑞芬太尼
声带息肉
Sevoflurane
Remifentanil
Vocal cord polyp
