摘要
目的 比较不同治疗方法治疗子宫内膜腺癌的疗效。方法 386例患者分别给予以下3种不同的治疗方法 ,(1)单纯手术 (手术组 ) 145例 ;(2 )手术 +放射治疗 (放疗 ,手术 +放疗组 ) 16 1例 ;(3)单纯放疗 (放疗组 ) 80例。治疗后随访均在 5年以上 ,观察各组的 5年生存率。结果 手术病理分期 (放疗组为临床分期 )Ⅰ期、Ⅱ期及Ⅲ～Ⅳ期的 5年生存率 ,手术组分别为 78 9% (5 6 /71)、6 1 0 %(2 5 /4 1)及 18 2 % (6 /33) ;手术 +放疗组分别为 75 0 % (33/4 4)、5 9 5 % (4 4/74)及 48 8% (2 1/4 3) ;放疗组分别为 34 8% (8/2 3)、18 8% (3/16 )及 0 0 % (0 /4 1)。Ⅰ期及Ⅱ期患者的 5年生存率 ,手术组与手术+放疗组比较 ,差异无显著性 (P >0 0 5 ) ,而Ⅲ～Ⅳ期手术 +放疗组明显高于手术组 (P <0 0 0 1) ;放疗组无论分期如何 ,其 5年生存率均显著低于手术组和手术 +放疗组 (P <0 0 0 1)。结论 子宫内膜腺癌应尽量争取以手术为主的治疗 。
Objective To compare the therapeutic effects of different remedis in patients with endometrial carcinoma Methods Total of 386 patients with metracarcinoma underwent 3 different treatments: (1) operation only 145 cases; (2) operation and complemental radiotherapy 161 cases; (3) radiotherapy only 80 cases Then they were followed up for 5 years and more Results The 5 year survival rates of operation group were 78 9% (56/71), 61 0% (25/41) and 18 2% (6/33) in stage Ⅰ, stage Ⅱ, and stage Ⅲ～Ⅳ respectively, for operation and complemental radiotherapy,they were 75 0% (33/44), 59 5% (44/74) and 48 8% (21/43), for radiotherapy, 34 8% (8/23), 18 8% (3/16) and 0 0% (0/41). There was no difference between operation group and operation plus radiotherapy in patients with stage Ⅰ and stage Ⅱ ( P >0 05). However the 5 year survival rates were significantly higher in operation plus complemental radiotherappy group and those only received operation in stage Ⅲ stage Ⅳ patients ( P <0 001) And no matter in what stages, the therapeutic effect was worse in radiotherapy group than other two groups ( P <0 001) Conclusion The remedis with operation as main measure are the best choice for metracarcinoma, radiotherapy merely is fit with those who can not be operated on
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2001年第3期153-155,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
子宫内膜肿瘤
腺癌
外科手术
放射治疗
Endometrial neoplasms
Adenocarcinoma
Surgical procedures, operation
Radiotherapy
