摘要
目的比较联合检测胃癌患者血清癌胚抗原(CEA)、糖类抗原(CA19-9、CA50、CA72-4)的临床意义。方法分别检测38例胃癌患者(胃癌组)、34例胃炎患者(胃炎组)、37例胃溃疡患者(胃溃疡组)及36例健康者(对照组)血清中CEA、CA19-9、CA50、CA72-4水平。结果 4项标志物检测的灵敏度分别为49.7%(CEA)、54.1%(CA19-9)、38.2%(CA50)、41.7%(CA72-4),联合检测CEA、CA19-9、CA50、CA72-4灵敏度为79.6%。结论联合检侧CEA、CA19-9、CA50、CA72-4对胃癌的诊断及疗效观察具有重要临床价值。
Objective To compare the clinical significance of combined detection of serum carcino-embryonic antigen （CEA）, carbohydrate antigens （CA19-9, CAS0 and CA72-4） in the di- agnosis of patients with gastric cancer. Methods The levels of serum CEA, CA19-9, CAS0 and CA72-4 in patients with gastric cancer （gastric group, n = 38）, gastritis （gastritis group, n = 34） and gastric ulcer （gastric ulcer group, n = 37） as well as healthy people （control group, n = 36） were detected respectively. Results The levels of sensitivity of CEA, CA19-9, CAS0 and CA72-4 were 49.7 %, 54.1%, 38.2 % and 41.7 % respectively, while the level of sensitivity of combined detection was 79.6 %. Conclusion Combined detection of CEA, CA19-9, CAS0 and CA72-4 shows a great clinical significance in the diagnosis and efficacy observation of patients with gastric cancer.
出处
《实用临床医药杂志》
CAS
2014年第5期1-3,共3页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11321496)
关键词
胃癌
癌胚抗原
糖类抗原19—9
糖类抗原50
糖类抗原72—4
gastric cancer
carcino-embryonic antigen
carbohydrate antigen 19-9
carbo-hydrate antigen 50
carbohydrate antigen 72-4
