摘要
嗜酸粒细胞性支气管炎（eosinophilicbronchitis，EB）是慢性咳嗽的主要病因之一，近年来其发病率呈上升趋势，国内其发病率为17．2％。EB是以慢性咳嗽为主要症状，其特点是肺部影像学、肺功能、气道反应性、PEF日间变异率均正常，而诱导痰嗜酸粒细胞比例增高，糖皮质激素治疗有效。病因尚不清楚，发病机制有待进一步研究。本文对EB的流行病学、病因、病理表现、发病机制、诊断、治疗和预后作一综述。
Eosinophilic bronchitis （EB） is one of the major causes of chronic cough. It is now showing a gradually rising morbidity, which accouts for 17.2% in our country as reported in a recent study published on Chest. EB is characterized by chronic cough in the presence of normal pulmonary imaging,normal spirometry, normal peak expiratory flow variability, and also in the absence of airway hyper-responsiveness. It is usually distinguished from others by induced sputum eosinophilia. As regard to treatments, corticosteroids is the first-line pharmacotherapy. Until now, the etiology and pathogenesis of EB still remains unclear. The aim of this article is to review the epidemiology, etiology, pathophysiology, pathogenesis,diagnosis,treatment and prognosis of this condition.
出处
《国际呼吸杂志》
2014年第11期866-869,共4页
International Journal of Respiration
