摘要
目的:分析高血压脑病(HE)的MRI表现与临床预后的关系,进一步提高对其MRI表现及发病机制的认识。材料与方法:回顾性分析了56例有详细临床、影像学资料的HE患者,收集患者血压、病因、影像学资料及随访情况,由至少2位高年资影像科医师共同阅片,评价其MRI异常表现、水肿程度和分级评定。结果:HE的MRI表现主要为脑水肿,病灶累及部位比例中顶叶、枕叶与其他各部位相比的差异均有统计学意义(Ρ<0.01);出现细胞毒性水肿16例(28.6%)、脑出血8例(14.2%),两者与脑水肿的较高分级具有相关性(Ρ<0.05)。结论:HE的MRI改变主要为脑水肿表现,出现细胞毒性脑水肿及脑出血提示脑血管内皮细胞损伤或破坏从而影响预后,因此认识HE的MRI不典型表现对其早期诊断和临床预后评价具有重要价值。
Purpose： To investigate the relationships between MRI findings in Hypertensive encephalopathy （HE） and clinical prognosis. Materials and Methods： Fifty -six patients with typical clinical symptoms and characteristic MRI findings of HE were retrospectively analyzed. The clinical records including of blood pressure, cause of disease were collected in all patients. The MRI findings and extent or degree of brain edema was graded by at least 2 experienced radiologists. Results：The main MRI findings of HE is edema. Brain lesions in the parietal or occipital regions and each other location were statistically significant （P 〈 0. 01 ）. Cytotoxic edema （ 16 cases, 28. 6% ） and intracranial hemorrhage （8 cases, 14. 2% ） were correlated with higher edema scores（ P 〈 0. 05）. Conclusion： The main manifestation of MRI is edama, and the atypical MRI findings appearances, such as cytotoxic edema and intracranial hemorrhage, reflect endothelial injury or disruption, which would be helpful for early diagnosis and prognosis evaluation.
出处
《现代医用影像学》
2014年第2期120-123,共4页
Modern Medical Imageology
关键词
高血压脑病
磁共振成像
脑水肿
预后
Hypertensive encephalopathy Magnetic resonance imaging Brain edema Prognosis
