摘要
目的 了解儿童系统性红斑狼疮的临床及实验室检查特征。方法 对 18例儿童系统性红斑狼疮与 5 4例成年人患者的临床特点进行对照研究。分析其首发症状、临床表现及实验改变。结果 儿童患者肾脏损害的严重程度比成人重 ,其它器官损害也多于成人 ,但无统计学意义 ,未成年人组C3 下降程度明显高于成年组 ,而CH50 降低的发生率明显高于成年组。结论 系统性红斑狼疮儿童患者临床及实验室检查与成人相比存在某些程度差异。
Objective To explore the fealures of systemic lupus erythematosus(SLE) in children.Methods 18 cases of SLE in children were reported.Their first sign and clinical manifestation,involvement of organs and laboratory findings were analysed and compared with another 54 cases of SLE in adults who were elected at random.Results The involvement of kindnrey in children was more severe than that in adults.The involvement of other organs in children was more common than that in adults,but there was no significant difference statistically.The decrease of complement 3 was more severe thar that in adults,and the incidence of decrease of CH50 in children was much higher than that in adults.Conclusion The clinical menifestations and laboratory examinations in SLE children have differences to some extent compared with that of adult cases.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2001年第1期16-18,共3页
The Chinese Journal of Dermatovenereology
