摘要
目的：探讨系统性红斑狼疮SLE脑病发生的临床相关因素。方法：对123例SLE患者的临床指征进行回顾性分析。结果：单因素分析示病程、肢端红斑坏死、光感性皮疹、血补体4（C4）、血白细胞减少、ALT升高、AST升高、尿红细胞升高、血清肌酐升高、血甘油三酯升高、血脂蛋白升高、A／G倒置、是否用肾上腺皮质激素治疗均与SLE脑病的发生相关（P ＜0．05；多因素回归分析（logistic analysis示血白细胞、尿红细胞、A／G倒置进入logistic多元回归方程（P ＜0．05）。结论：上述临床指征与SLE脑病的发生有关，其中血白细胞、尿红细胞、A／G倒置是SLE患者发生脑病最重要的临床相关因素。
Objective To study the risk factors of encephalopathy in systemic lupus erythematosus． Methods 123 SLE patients of were studied retrospectively． Results Single factor correlation analysis showed that 13 factors including course of disease extremity erythema necrosis light sensitivity eruption serum complement C4 white blood cellWBC serum glutamic-pyruvic transaminaseALT，glutamic-oxalacetic transaminaseAST， urine red blood cellRBC，serum creatinine triglyceride lipoprotein serum albumin／globulinA／G and hormone therapy were related to the onset of encephalopathy． Only three factors including WBC urine RBC and serum A／G entered the multi-factor logistic equation． Conclusions The above-mentioned 13 factors are related to the onset of encephalopathy of SLE WBC urine RBC and serum A／G are among the most important risk factors．
出处
《新医学》
北大核心
2001年第3期144-146,共3页
Journal of New Medicine
关键词
系统性红斑狼疮
中枢神经系统疾病
发病原因
脑病
病例报告
Lupus Erythematosus Systemic Encephalopathy Risk Factor Single factor analysis Multi-factors logistic regression analysis
