摘要
目的:探讨痰瘀互结证对高血压患者血浆同型半胱氨酸(Hcy)水平的影响。方法:符合纳入标准痰瘀互结证高血压患者83例,非痰瘀互结证高血压患者66例,并与30例健康体检者对照。测定三组患者空腹血浆同型半胱氨酸水平。结果:痰瘀互结证组同型半胱氨酸水平显著高于非痰瘀互结证组和对照组(P<0.01),非痰瘀互结证组与对照组比较差异无统计学意义(P>0.05),3级高血压组同型半胱氨酸水平显著高于1级高血压组和2级高血压组(P<0.01),1级高血压组与2级高血压组比较差异无统计学意义(P>0.05)。结论:痰瘀互结证高血压患者空腹血浆同型半胱氨酸水平显著高于非痰瘀互结证组和对照组,或可为高血压患者痰瘀互结证证型判定提供客观依据;3级高血压组患者空腹血浆同型半胱氨酸水平显著高于1级高血压组和2级高血压组,同型半胱氨酸代谢障碍可能是促使高血压进展的环节之一。
Objective： Discuss the influence of phlegm and blood stasis on the homocysteine（ Hcy） levels of hyperpietics. Methods： Intake 83 phlegm and blood stasis type hyperpietics and 66 no-phlegm and blood stasis type hyperpietics,comparing with 30 healthy subjects. Test the fasting plasma homocysteine levels of three groups. Results： The homocysteine levels of the phlegm and blood stasis type hyperpietics were significantly higher than both of the no-phlegm and blood stasis type hyperpietics and healthy subjects（ P ＆lt; 0. 01）,and there was no statistically significant difference between the no-phlegm and blood stasis type hyperpietics and healthy subjects（ P ＆gt; 0. 05）; the homocysteine levels of the grade 3 hyperpietics were significantly higher than both of the grade 1 hyperpietics and the grade 2 hyperpietics（ P ＆lt; 0. 01）,and there was no statistically significant difference between the grade 1 hyperpietics and the grade 2 hyperpietics（ P ＆gt; 0. 05）. Conclusion： The homocysteine levels of the phlegm and blood stasis type hyperpietics are significantly higher than both of the no-phlegm and blood stasis type hyperpietics and healthy subjects,which may provide objective basis on syndrome judging of phlegm and blood stasis type hyperpietics. The homocysteine levels of the grade 3 hyperpietics are significantly higher than both of the grade 1 hyperpietics and the grade 2 hyperpietics. Hcy metabolic disorders may be the one link on aggravation of the hypertension.
出处
《中医药信息》
2014年第3期88-90,共3页
Information on Traditional Chinese Medicine
基金
天津市中医药管理局中医中西医结合科研课题(No.13172)
关键词
痰瘀互结证
高血压
同型半胱氨酸
Syndrome of phlegm and blood stasis
Hypertension
Homocysteine
