摘要
用各国临床微生物学实验广泛采用的K-B纸片扩散药敏试验方法(美国NCCLS标准),对阿莫西林胶囊等8种腹泻药的体外抑菌活性作对比分析,可以得单方制剂在短时间内表现出较好的抑菌效果,而复方制剂则体现较长时间的持续抑菌作用。基于此,对于普通的肠杆菌感染,施用单方制剂,不仅足以治疗,也能最大程度减少对人体的毒副作用;对于较为复杂严重的腹泻,则需要选择复方制剂,既能较为及时的缓解症状,又能持久的治疗病症。
Eight typical diarrhea medicines, such as AmoxiciUin Capsules, were choosed to be tested in vitro antibacterial activity to E.coli strains using Bauer-Kirby disc agar diffusion method （the United States NCCLS standards）. Through the comparative analysis of their antibacterial activity, the unilateral drugs showed better antibacterial activity in a short period of time, while the combination drugs presented persistent inhibiting effects of long time. So, for the common Enterobacteriaceae enteric infections, the unilateral drugs was available not only to the treatment but reduce the toxic side effects on the human body to the maximum extent; For more complicated severe diarrhea, the combination drugs were suggested, which could more timely relieve symptoms, and gave lasting treatment of the disease.
基金
贵州省应用化学特色重点实验室项目
关键词
腹泻药
大肠杆菌
抑菌活性
比较分析
Diarrhea Medicine
E.coli Strains
Antibacterial Activity
Comparative Analysis
