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抗凝血酶Ⅲ和纤维蛋白原测定与心肌梗死的相关性研究 被引量:4

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摘要 目的探讨抗凝血酶Ⅲ(AT-Ⅲ)和纤维蛋白原(Fib-C)测定与心肌梗死的相关性。方法对23例急性ST段抬高型心肌梗死(STEMI)、29例非ST段抬高型心肌梗死(NSTEMI)和100例健康体检者(对照组)的血浆中的AT-Ⅲ活性与Fib-C浓度进行测定分析。结果 STEMI组与NSTEMI组的AT-Ⅲ活性及Fib-C浓度分别为(75.909±16.865)%与(3.784±0.527)g/L及(83.690±15.048)%与(3.488±0.933)g/L。经SPSS v17.0统计软件处理后,STEMI组与NSTEMI组的AT-Ⅲ活性均低于对照组(P<0.05);STEMI组与NSTEMI组的Fib-C浓度均高于对照组(P<0.05);STEMI组的AT-Ⅲ活性低于NSTEMI组(P<0.05);STEMI组的Fib-C浓度高于NSTEMI组(P<0.05)。结论 AT-Ⅲ活性降低及Fib-C浓度升高与心肌梗死患者处于高凝状态或血栓形成密切相关;并通过测定有助于了解二者在不同类型的心肌梗死的发生、发展所起的作用,从而协助临床的诊断、治疗及预后的判断。
出处 《国际检验医学杂志》 CAS 2014年第10期1359-1360,共2页 International Journal of Laboratory Medicine
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