摘要
目的：观察肌肉注射咪达唑仑治疗儿童急性惊厥的疗效及安全性。方法：选取我院儿科就诊的急性惊厥患儿100例,随机分为治疗组与对照组各50例,治疗组肌肉注射咪达唑仑0.2~0.3 mg/kg,对照组静脉注射地西泮0.3~0.5 mg/kg。结果：治疗组有效率92.0%,对照组有效率96.0%,两组比较差异无统计学意义（P〉0.05）;治疗组患儿惊厥平均控制时间为（3.37±1.51）min,对照组惊厥平均控制时间为（2.96±1.85）min,两组惊厥控制有效患儿平均控制时间比较差异无统计学意义（P〉0.05）。结论：肌肉注射咪达唑仑治疗儿童急性惊厥起效快、疗效可靠,安全性高。
Objective： To observe the effect and security of midazolam intramuscular injection for treating acute convulsion in children. Methods： One hundred children with acute convulsion were randomly divided into a treatment group and a control group with 50 cases each. The treatment group received midazolam intramuscular injection O. 2 - O. 3 mg/kg, while the control group were treated with intravenous injection of diazepam 0.3 - 0.5 mg/kg. Results： The effective rate of the treatment group was 92.0%, while it was 96.0% of the control group. There were no significant differences between the two groups （P〉0.05）. In the treatment group, the average time of convulsion control was （3.37 ± 1.51 ） minutes, while in the control group it was （2.96± 1.85 ） minutes. It had no significant difference （P〉O. 05 ）. Conclusions： The midazolam intramuscular injection for treating acute convulsion in children is effective and safe.
出处
《儿科药学杂志》
CAS
2014年第6期13-15,共3页
Journal of Pediatric Pharmacy
关键词
咪达唑仑
地西泮
惊厥
儿童
Midazolam
Diazepam
Convulsion
Children
