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PCSK9在血脂调节中的研究进展 被引量:9

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摘要 血脂异常是最重要的心血管疾病危险因素之一,降脂可减少动脉粥样硬化及其并发症的发生发展。他汀类药物能有效降脂,并已形成标准的治疗方案。然而,许多患者在最大耐受剂量的情况下血脂仍不能达标。人前蛋白转化酶枯草溶菌素9(PCSK9)基因与血脂代谢密切相关,它通过降解低密度脂蛋白受体(LDL-R)升高血胆固醇水平。
作者 韩旭 龙明智
出处 《国际心血管病杂志》 2014年第3期176-178,共3页 International Journal of Cardiovascular Disease
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