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邻苯二甲酸酯类的雄性生殖毒性研究进展 被引量：6

Progress of phthalate acid esters effect on male reproductive toxicity
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摘要 邻苯二甲酸酯类化合物(phthalate acid esters,PAEs)是一类重要的环境内分泌干扰物,在人群中广泛、持续暴露,对雄性动物的胚胎和生殖系统发育以及生殖功能等具有潜在的生殖毒性。文中就PAEs的雄性生殖毒性研究进展及相关热点问题进行综述。 Phthalate acid esters （PAEs） are a kind of important environmental endocrine disrupting compounds. Because the public are exposed to PAEs continuously, the potential reproductive toxicity effect on development of reproductive system in male animal causes increasing concerns. This article reviews the male reproductive toxicity and other related problems of PAEs.
作者 秦晓东 袁欣然 李冬梅 韩晓冬
机构地区 南京大学医学院免疫与生殖生物学实验室
出处 《医学研究生学报》 CAS 北大核心 2014年第5期531-535,共5页 Journal of Medical Postgraduates
基金 国家自然科学基金(21377052) 江苏省自然科学基金(BK20131281) 南京大学大学生创新创业训练计划项目(G1210284113)
关键词 邻苯二甲酸酯 雄性生殖毒性 风险评价 Phthalate acid esters Male reproductive toxicity Risk assessment
分类号 R114 [医药卫生—卫生毒理学]
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参考文献42

  • 1Meeker JD. Exposure to environmental endocrine disrupting com- pounds and men's health [ J ]. Maturitas, 2010, 66 ( 3 ) : 236- 241. 被引量：1
  • 2Kambia N, Dine T, Gressier B, et al. Strong variability of di ( 2- ethylhexyl) phthalate (DEHP) plasmatic rate in infants and chil- dren undergoing 12-hour cyclic parenteral nutrition [ J ]. JPEN J Parenter Enteral Nutr, 2013, 37(2): 229-235. 被引量：1
  • 3Shaffer CB, Carpenter CP, Smyth Jr HF, et al. Acute and suba- cute toxicity of di (2-ethylhexyl) phthalate with note upon its me- tabolism[J]. J Ind Hyg Toxicol, 1945, 27(5) : 130-135. 被引量：1
  • 4Gangolli SD. Testicular effects of phthalate esters [ J ]. Environ Health Perspect, 1982, 45: 77-84. 被引量：1
  • 5Agarwal DK, Maronpot RR, Lamb JC, et al. Adverse effects of butyl benzyl phthalate on the reproductive and hematopoietic sys- tems of male rats[ J]. Toxicology, 1985, 35 (3) : 189-206. 被引量：1
  • 6Pant N, Pant A, Shukla M, et al. Environmental and experimen- tal exposure of phthalate esters : the toxicological consequence on human sperm[J]. Hum Exp Toxicol, 2011, 30(6) : 507-514. 被引量：1
  • 7Gray LE, Ostby J, Furr J, et al. Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat [ J ]. Toxicol Sci, 2000, 58(2) : 350-365. 被引量：1
  • 8Li M, Qiu L, Zhang Y, et al. Dose-related effect by maternal exposure to di-(2-ethylhexyl) phthalate plasticizer on inducing hypospadiac male rats [ J ]. Environ Toxicol Pharmacol, 2013,35 (1): 55-60. 被引量：1
  • 9Saillenfait AM, Gallissot F, Sabat6 JP, et al. Prenatal develop- mental toxicity studies on diundecyl and ditridecyl phthalates in Sprague-Dawley rats [ J]. Reprod Toxicol, 2013, 37 : 49-55. 被引量：1
  • 10Dorostghoal M, Moazedi AA, Zardkaf A. Long-term effects of maternal exposure to Di (2-ethylhexyl) Phthalate on sperm and testicular parameters in Wistar rats offspring [ J ]. Iran J Reprod Med, 2012, 10(1): 7-14. 被引量：1

二级参考文献35

  • 1虎明明,刘秀芳,李杰,关霞,宁艳花.辛硫磷和灭多威对雄性大鼠生殖系统的联合毒性作用[J].癌变．畸变．突变,2008,20(5):389-392. 被引量：7
  • 2王慧阳,孟紫强,常凤滨.二氧化硫体内衍生物对雄性小鼠精子的毒性效应[J].应用与环境生物学报,2006,12(3):363-366. 被引量：21
  • 3邱志群,舒为群,曹佳.我国水中有机物及部分持久性有机物污染现状[J].癌变．畸变．突变,2007,19(3):188-193. 被引量：32
  • 4Harris CA, Henttu P,ParkerMG,et al.The estrogenic activity of phthalate- esters in vitro[J].Environ Health Perspect, 1997,105:802-811. 被引量：1
  • 5Moore RW, Rudy TA,Lin TM, et al,Abnormalities of sexual development in male rats with utero and lactational exposure to the antiandrogenic plastieizer di(2-ethylhexyl)phihalate [J].Environ Health Perspect, 2001,109 : 229-237. 被引量：1
  • 6Stoker TE , Parks LG, Gray LE, et al. Edocrine disrupting chemicals : prepubertal exposures and effects on sexual maturation and thyroid function in the male rat: a focus on the EDSTAC recommendations [J]. Crit Rev Toxieol, 2000,30:197-252. 被引量：1
  • 7庄志雄,王心如,周宗灿.毒理学基础[M].5版.北京:人民卫生出版社,2007:25-26. 被引量：1
  • 8Howdeshell KL,Wilson VS,Furr J.A mixture of five phthalateesters inhibits fetal testicular testosterone production in the spra-gue-dawley rat in a cumulative,dose-additive manner. Toxi-col Sci . 2008 被引量：1
  • 9J Borch,SB Metzdorff,AM Vingaard,L Brokken,M Dalgaard.Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis. Toxicology . 2006 被引量：1
  • 10Shirota M,Saito Y,i K,et a1.Influence of di-(2-ethylhe-xy1)phthalate on fetal testicular development by oraladministration to pregnant rats. Toxicological Sciences . 2005 被引量：1

共引文献11

同被引文献55

  • 1王玉邦,宋玲,朱正平,陈建锋,何俊,刘茹,王心如.邻苯二甲酸二丁酯对大鼠睾丸生化酶及脂质过氧化的影响[J].中华男科学杂志,2004,10(10):729-733. 被引量：8
  • 2乔丽丽,郑力行,蔡德培.上海市女童血清中邻苯二甲酸二丁酯和邻苯二甲酸-2-乙基己酯水平与性早熟关系研究[J].卫生研究,2007,36(1):93-95. 被引量：64
  • 3王婷,郑玉建,吴顺华,张杰.砷致小鼠脂质过氧化及锌、硒对其的干预研究[J].新疆医科大学学报,2007,30(6):551-553. 被引量：3
  • 4Bergh C, Torgrip R, Emenius G, et al. Organophosphate and phthalate esters in airand settled dust-a multi- location indoor study [J]. Indoor Air, 2011, 21 (1): 67-76. 被引量：1
  • 5Meeker JD. Exposure to environmental endocrine disrupting compounds and men's health [J]. Maturitas, 2010, 66 (3): 236-241. 被引量：1
  • 6Kambia N, Dine T, Gressier B, et al. Strong variability of di (2-ethylhexyl) phthalate (DEHP) plasmatic rate in infants and children undergoing 12-hour cyclic parenteral nutrition [J]. J Parenteral Enteral Nutrit, 2013, 37 (2): 229-235. 被引量：1
  • 7Hines C J, Hopf NB, Deddens JA, et al. Occupational exposure to diisononyl phthalate (DiNP) in polyvinyl chloride processing operations [J]. Int Arch Occup Envir Health, 2012, 85 (3): 317-325. 被引量：1
  • 8Yao PL, Lin YC, Richburg JH. Transcriptional suppression of Sertoli cell Timp2 in rodents following mono-(2-ethylhexyl) phthalate exposure is regulated by CEBPA and MYC [J]. Biol Reprod, 2011, 85 (6): 1203-1215. 被引量：1
  • 9Pant N, Pant A, Shukla M, et al. Environmental and experimental exposure of phthalate esters: the toxicological eonsequenee on human sperm [J]. Hum Exp Toxicol, 2011, 30 (6): 507-514. 被引量：1
  • 10Erdos Z, Pearson K, Goedken M, et al. Inhihin B response to testicular toxicants hexachlorophene, ethane dimethanesulfonate, di-(n-butyl)-phthalate, nitrofurazone, DL-ethionine, 17-alpha ethinylestradiol, 2, 5-hexanedione, or earbendazim following short-term dosing in male rats [J].Birth Defects Res B Develop Reprod Toxieol, 2013, 98 (1): 41-53. 被引量：1

引证文献6

二级引证文献21

医学研究生学报
2014年 第5期

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